Chin AC - Search Results

1

Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma.

Wang ES, Wu K, Chin AC, Chen-Kiang S, Pongracz K, Gryaznov S, Moore MA. Wang ES, et al. Among authors: chin ac. Blood. 2004 Jan 1;103(1):258-66. doi: 10.1182/blood-2003-02-0546. Epub 2003 Sep 11. Blood. 2004. PMID: 12969977 Free article.

2

Oligonucleotide N3' --> P5' thio-phosphoramidate telomerase template antagonists as potential anticancer agents.

Gryaznov S, Asai A, Oshima Y, Yamamoto Y, Pongracz K, Pruzan R, Wunder E, Piatyszek M, Li S, Chin A, Harley C, Akinaga S, Yamashita Y. Gryaznov S, et al. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):577-81. doi: 10.1081/NCN-120021958. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565232

3

Novel short oligonucleotide conjugates as inhibitors of human telomerase.

Pongracz K, Li S, Herbert BS, Pruzan R, Wunder E, Chin A, Piatyszek M, Shay J, Gryaznov SM. Pongracz K, et al. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1627-9. doi: 10.1081/NCN-120023085. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565482

4

A novel telomerase template antagonist (GRN163) as a potential anticancer agent.

Asai A, Oshima Y, Yamamoto Y, Uochi TA, Kusaka H, Akinaga S, Yamashita Y, Pongracz K, Pruzan R, Wunder E, Piatyszek M, Li S, Chin AC, Harley CB, Gryaznov S. Asai A, et al. Among authors: chin ac. Cancer Res. 2003 Jul 15;63(14):3931-9. Cancer Res. 2003. PMID: 12873987

5

Lipid modification of GRN163, an N3'-->P5' thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition.

Herbert BS, Gellert GC, Hochreiter A, Pongracz K, Wright WE, Zielinska D, Chin AC, Harley CB, Shay JW, Gryaznov SM. Herbert BS, et al. Among authors: chin ac. Oncogene. 2005 Aug 4;24(33):5262-8. doi: 10.1038/sj.onc.1208760. Oncogene. 2005. PMID: 15940257

6

Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma.

Djojosubroto MW, Chin AC, Go N, Schaetzlein S, Manns MP, Gryaznov S, Harley CB, Rudolph KL. Djojosubroto MW, et al. Among authors: chin ac. Hepatology. 2005 Nov;42(5):1127-36. doi: 10.1002/hep.20822. Hepatology. 2005. PMID: 16114043

7

Telomerase inhibitors--oligonucleotide phosphoramidates as potential therapeutic agents.

Gryaznov S, Pongracz K, Matray T, Schultz R, Pruzan R, Aimi J, Chin A, Harley C, Shea-Herbert B, Shay J, Oshima Y, Asai A, Yamashita Y. Gryaznov S, et al. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):401-10. doi: 10.1081/NCN-100002314. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563055

8

Telomerase inhibitor GRN163L inhibits myeloma cell growth in vitro and in vivo.

Shammas MA, Koley H, Bertheau RC, Neri P, Fulciniti M, Tassone P, Blotta S, Protopopov A, Mitsiades C, Batchu RB, Anderson KC, Chin A, Gryaznov S, Munshi NC. Shammas MA, et al. Leukemia. 2008 Jul;22(7):1410-8. doi: 10.1038/leu.2008.81. Epub 2008 May 1. Leukemia. 2008. PMID: 18449204 Free PMC article.

9

Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes.

Fauce SR, Jamieson BD, Chin AC, Mitsuyasu RT, Parish ST, Ng HL, Kitchen CM, Yang OO, Harley CB, Effros RB. Fauce SR, et al. Among authors: chin ac. J Immunol. 2008 Nov 15;181(10):7400-6. doi: 10.4049/jimmunol.181.10.7400. J Immunol. 2008. PMID: 18981163 Free PMC article.

10

Inhibiting IP6K1 confers atheroprotection by elevating circulating apolipoprotein A-I.

Liu X, Zhang Z, Aguirre T, Shipton ML, Fu L, Du J, Furkert D, Qi J, Chin AC, Riley AM, Liu T, Zhang X, Potter BVL, Fiedler D, Zhu Y, Fu C. Liu X, et al. Among authors: chin ac. Metabolism. 2025 Feb;163:156098. doi: 10.1016/j.metabol.2024.156098. Epub 2024 Dec 4. Metabolism. 2025. PMID: 39643078 Free PMC article.

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