Fukumoto H - Search Results

1

APOE epsilon 3/ epsilon 4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer's disease diagnosis.

Fukumoto H, Ingelsson M, Gårevik N, Wahlund LO, Nukina N, Yaguchi Y, Shibata M, Hyman BT, Rebeck GW, Irizarry MC. Fukumoto H, et al. Exp Neurol. 2003 Sep;183(1):249-53. doi: 10.1016/s0014-4886(03)00088-8. Exp Neurol. 2003. PMID: 12957508

2

Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain.

Ingelsson M, Fukumoto H, Newell KL, Growdon JH, Hedley-Whyte ET, Frosch MP, Albert MS, Hyman BT, Irizarry MC. Ingelsson M, et al. Among authors: fukumoto h. Neurology. 2004 Mar 23;62(6):925-31. doi: 10.1212/01.wnl.0000115115.98960.37. Neurology. 2004. PMID: 15037694

3

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease.

Fukumoto H, Cheung BS, Hyman BT, Irizarry MC. Fukumoto H, et al. Arch Neurol. 2002 Sep;59(9):1381-9. doi: 10.1001/archneur.59.9.1381. Arch Neurol. 2002. PMID: 12223024

4

Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels.

Fukumoto H, Tennis M, Locascio JJ, Hyman BT, Growdon JH, Irizarry MC. Fukumoto H, et al. Arch Neurol. 2003 Jul;60(7):958-64. doi: 10.1001/archneur.60.7.958. Arch Neurol. 2003. PMID: 12873852

5

Decreased levels of BDNF protein in Alzheimer temporal cortex are independent of BDNF polymorphisms.

Lee J, Fukumoto H, Orne J, Klucken J, Raju S, Vanderburg CR, Irizarry MC, Hyman BT, Ingelsson M. Lee J, et al. Among authors: fukumoto h. Exp Neurol. 2005 Jul;194(1):91-6. doi: 10.1016/j.expneurol.2005.01.026. Exp Neurol. 2005. PMID: 15899246

6

Coordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: relationship to formic acid extractable abeta42 levels.

Matsui T, Ramasamy K, Ingelsson M, Fukumoto H, Conrad C, Frosch MP, Irizarry MC, Yuan J, Hyman BT. Matsui T, et al. Among authors: fukumoto h. J Neuropathol Exp Neurol. 2006 May;65(5):508-15. doi: 10.1097/01.jnen.0000229238.05748.12. J Neuropathol Exp Neurol. 2006. PMID: 16772874

7

Plasma amyloid beta-protein and C-reactive protein in relation to the rate of progression of Alzheimer disease.

Locascio JJ, Fukumoto H, Yap L, Bottiglieri T, Growdon JH, Hyman BT, Irizarry MC. Locascio JJ, et al. Among authors: fukumoto h. Arch Neurol. 2008 Jun;65(6):776-85. doi: 10.1001/archneur.65.6.776. Arch Neurol. 2008. PMID: 18541797 Free PMC article.

8

Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels.

Fukumoto H, Deng A, Irizarry MC, Fitzgerald ML, Rebeck GW. Fukumoto H, et al. J Biol Chem. 2002 Dec 13;277(50):48508-13. doi: 10.1074/jbc.M209085200. Epub 2002 Oct 15. J Biol Chem. 2002. PMID: 12384498 Free article.

9

Beta-secretase activity increases with aging in human, monkey, and mouse brain.

Fukumoto H, Rosene DL, Moss MB, Raju S, Hyman BT, Irizarry MC. Fukumoto H, et al. Am J Pathol. 2004 Feb;164(2):719-25. doi: 10.1016/s0002-9440(10)63159-8. Am J Pathol. 2004. PMID: 14742275 Free PMC article.

10

Expression of APP pathway mRNAs and proteins in Alzheimer's disease.

Matsui T, Ingelsson M, Fukumoto H, Ramasamy K, Kowa H, Frosch MP, Irizarry MC, Hyman BT. Matsui T, et al. Among authors: fukumoto h. Brain Res. 2007 Aug 3;1161:116-23. doi: 10.1016/j.brainres.2007.05.050. Epub 2007 Jun 5. Brain Res. 2007. PMID: 17586478

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