Leiper JM - Search Results

1

Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension.

Millatt LJ, Whitley GS, Li D, Leiper JM, Siragy HM, Carey RM, Johns RA. Millatt LJ, et al. Among authors: leiper jm. Circulation. 2003 Sep 23;108(12):1493-8. doi: 10.1161/01.CIR.0000089087.25930.FF. Epub 2003 Sep 2. Circulation. 2003. PMID: 12952847

2

all-trans-Retinoic acid increases nitric oxide synthesis by endothelial cells: a role for the induction of dimethylarginine dimethylaminohydrolase.

Achan V, Tran CT, Arrigoni F, Whitley GS, Leiper JM, Vallance P. Achan V, et al. Among authors: leiper jm. Circ Res. 2002 Apr 19;90(7):764-9. doi: 10.1161/01.res.0000014450.40853.2b. Circ Res. 2002. PMID: 11964368

3

Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase.

Achan V, Broadhead M, Malaki M, Whitley G, Leiper J, MacAllister R, Vallance P. Achan V, et al. Arterioscler Thromb Vasc Biol. 2003 Aug 1;23(8):1455-9. doi: 10.1161/01.ATV.0000081742.92006.59. Epub 2003 Jun 12. Arterioscler Thromb Vasc Biol. 2003. PMID: 12805079 Clinical Trial.

4

Active site mutant dimethylarginine dimethylaminohydrolase 1 expression confers an intermediate tumour phenotype in C6 gliomas.

Boult JK, Walker-Samuel S, Jamin Y, Leiper JM, Whitley GS, Robinson SP. Boult JK, et al. Among authors: leiper jm. J Pathol. 2011 Nov;225(3):344-52. doi: 10.1002/path.2904. Epub 2011 May 18. J Pathol. 2011. PMID: 21590769

5

Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by hypobaric hypoxia.

Arrigoni FI, Vallance P, Haworth SG, Leiper JM. Arrigoni FI, et al. Among authors: leiper jm. Circulation. 2003 Mar 4;107(8):1195-201. doi: 10.1161/01.cir.0000051466.00227.13. Circulation. 2003. PMID: 12615801 Free article.

6

Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases.

Leiper JM, Santa Maria J, Chubb A, MacAllister RJ, Charles IG, Whitley GS, Vallance P. Leiper JM, et al. Biochem J. 1999 Oct 1;343 Pt 1(Pt 1):209-14. Biochem J. 1999. PMID: 10493931 Free PMC article.

7

Isoform-specific regulation by N(G),N(G)-dimethylarginine dimethylaminohydrolase of rat serum asymmetric dimethylarginine and vascular endothelium-derived relaxing factor/NO.

Wang D, Gill PS, Chabrashvili T, Onozato ML, Raggio J, Mendonca M, Dennehy K, Li M, Modlinger P, Leiper J, Vallance P, Adler O, Leone A, Tojo A, Welch WJ, Wilcox CS. Wang D, et al. Circ Res. 2007 Sep 14;101(6):627-35. doi: 10.1161/CIRCRESAHA.107.158915. Epub 2007 Aug 2. Circ Res. 2007. PMID: 17673667

8

cAMP phosphodiesterase inhibitors increases nitric oxide production by modulating dimethylarginine dimethylaminohydrolases.

Pullamsetti SS, Savai R, Schaefer MB, Wilhelm J, Ghofrani HA, Weissmann N, Schudt C, Fleming I, Mayer K, Leiper J, Seeger W, Grimminger F, Schermuly RT. Pullamsetti SS, et al. Circulation. 2011 Mar 22;123(11):1194-204. doi: 10.1161/CIRCULATIONAHA.110.941484. Epub 2011 Mar 7. Circulation. 2011. PMID: 21382892

9

Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine.

Ghebremariam YT, LePendu P, Lee JC, Erlanson DA, Slaviero A, Shah NH, Leiper J, Cooke JP. Ghebremariam YT, et al. Circulation. 2013 Aug 20;128(8):845-53. doi: 10.1161/CIRCULATIONAHA.113.003602. Epub 2013 Jul 3. Circulation. 2013. PMID: 23825361 Free PMC article.

10

Endothelial Dimethylarginine Dimethylaminohydrolase 1 Is an Important Regulator of Angiogenesis but Does Not Regulate Vascular Reactivity or Hemodynamic Homeostasis.

Dowsett L, Piper S, Slaviero A, Dufton N, Wang Z, Boruc O, Delahaye M, Colman L, Kalk E, Tomlinson J, Birdsey G, Randi AM, Leiper J. Dowsett L, et al. Circulation. 2015 Jun 23;131(25):2217-25. doi: 10.1161/CIRCULATIONAHA.114.015064. Epub 2015 Apr 24. Circulation. 2015. PMID: 25910799

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