Rosen H - Search Results

1

Sphingosine 1-phosphate pathway therapeutics: a lipid ligand-receptor paradigm.

Rosen H, Liao J. Rosen H, et al. Curr Opin Chem Biol. 2003 Aug;7(4):461-8. doi: 10.1016/s1367-5931(03)00085-1. Curr Opin Chem Biol. 2003. PMID: 12941420 Review.

2

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists.

Mandala S, Hajdu R, Bergstrom J, Quackenbush E, Xie J, Milligan J, Thornton R, Shei GJ, Card D, Keohane C, Rosenbach M, Hale J, Lynch CL, Rupprecht K, Parsons W, Rosen H. Mandala S, et al. Among authors: rosen h. Science. 2002 Apr 12;296(5566):346-9. doi: 10.1126/science.1070238. Epub 2002 Mar 28. Science. 2002. PMID: 11923495

3

Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist.

Rosen H, Alfonso C, Surh CD, McHeyzer-Williams MG. Rosen H, et al. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10907-12. doi: 10.1073/pnas.1832725100. Epub 2003 Sep 3. Proc Natl Acad Sci U S A. 2003. PMID: 12954982 Free PMC article.

4

Egress: a receptor-regulated step in lymphocyte trafficking.

Rosen H, Sanna G, Alfonso C. Rosen H, et al. Immunol Rev. 2003 Oct;195:160-77. doi: 10.1034/j.1600-065x.2003.00068.x. Immunol Rev. 2003. PMID: 12969317 Review.

5

Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate.

Sanna MG, Liao J, Jo E, Alfonso C, Ahn MY, Peterson MS, Webb B, Lefebvre S, Chun J, Gray N, Rosen H. Sanna MG, et al. Among authors: rosen h. J Biol Chem. 2004 Apr 2;279(14):13839-48. doi: 10.1074/jbc.M311743200. Epub 2004 Jan 19. J Biol Chem. 2004. PMID: 14732717 Free article.

6

S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate.

Jo E, Sanna MG, Gonzalez-Cabrera PJ, Thangada S, Tigyi G, Osborne DA, Hla T, Parrill AL, Rosen H. Jo E, et al. Among authors: rosen h. Chem Biol. 2005 Jun;12(6):703-15. doi: 10.1016/j.chembiol.2005.04.019. Chem Biol. 2005. PMID: 15975516

7

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network.

Rosen H, Goetzl EJ. Rosen H, et al. Nat Rev Immunol. 2005 Jul;5(7):560-70. doi: 10.1038/nri1650. Nat Rev Immunol. 2005. PMID: 15999095 Review.

8

Chemical approaches to the lysophospholipid receptors.

Rosen H. Rosen H. Prostaglandins Other Lipid Mediat. 2005 Sep;77(1-4):179-84. doi: 10.1016/j.prostaglandins.2004.09.011. Prostaglandins Other Lipid Mediat. 2005. PMID: 16099402 Review.

9

Lysophospholipid receptors as potential drug targets in tissue transplantation and autoimmune diseases.

Chun J, Rosen H. Chun J, et al. Among authors: rosen h. Curr Pharm Des. 2006;12(2):161-71. doi: 10.2174/138161206775193109. Curr Pharm Des. 2006. PMID: 16454733 Review.

10

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

Sanna MG, Wang SK, Gonzalez-Cabrera PJ, Don A, Marsolais D, Matheu MP, Wei SH, Parker I, Jo E, Cheng WC, Cahalan MD, Wong CH, Rosen H. Sanna MG, et al. Among authors: rosen h. Nat Chem Biol. 2006 Aug;2(8):434-41. doi: 10.1038/nchembio804. Epub 2006 Jul 9. Nat Chem Biol. 2006. PMID: 16829954

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