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A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain.
O'Brien JA, Lemaire W, Wittmann M, Jacobson MA, Ha SN, Wisnoski DD, Lindsley CW, Schaffhauser HJ, Rowe B, Sur C, Duggan ME, Pettibone DJ, Conn PJ, Williams DL Jr. O'Brien JA, et al. Among authors: pettibone dj. J Pharmacol Exp Ther. 2004 May;309(2):568-77. doi: 10.1124/jpet.103.061747. Epub 2004 Jan 27. J Pharmacol Exp Ther. 2004. PMID: 14747613
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models.
Kinney GG, O'Brien JA, Lemaire W, Burno M, Bickel DJ, Clements MK, Chen TB, Wisnoski DD, Lindsley CW, Tiller PR, Smith S, Jacobson MA, Sur C, Duggan ME, Pettibone DJ, Conn PJ, Williams DL Jr. Kinney GG, et al. Among authors: pettibone dj. J Pharmacol Exp Ther. 2005 Apr;313(1):199-206. doi: 10.1124/jpet.104.079244. Epub 2004 Dec 17. J Pharmacol Exp Ther. 2005. PMID: 15608073
Generation and characterization of a human bradykinin receptor B1 transgenic rat as a pharmacodynamic model.
Hess JF, Ransom RW, Zeng Z, Chang RS, Hey PJ, Warren L, Harrell CM, Murphy KL, Chen TB, Miller PJ, Lis E, Reiss D, Gibson RE, Markowitz MK, DiPardo RM, Su DS, Bock MG, Gould RJ, Pettibone DJ. Hess JF, et al. Among authors: pettibone dj. J Pharmacol Exp Ther. 2004 Aug;310(2):488-97. doi: 10.1124/jpet.104.066886. Epub 2004 Mar 29. J Pharmacol Exp Ther. 2004. PMID: 15051800
Pharmacological characterization and radioligand binding properties of a high-affinity, nonpeptide, bradykinin B1 receptor antagonist.
Ransom RW, Harrell CM, Reiss DR, Murphy KL, Chang RS, Hess JF, Miller PJ, O'Malley SS, Hey PJ, Kunapuli P, Su DS, Markowitz MK, Wallace MA, Raab CE, Jones AN, Dean DC, Pettibone DJ, Freidinger RM, Bock MG. Ransom RW, et al. Among authors: pettibone dj. Eur J Pharmacol. 2004 Sep 19;499(1-2):77-84. doi: 10.1016/j.ejphar.2004.07.104. Eur J Pharmacol. 2004. PMID: 15363953
109 results