Mackenzie PI - Search Results

1

Isoform selectivity and kinetics of morphine 3- and 6-glucuronidation by human udp-glucuronosyltransferases: evidence for atypical glucuronidation kinetics by UGT2B7.

Stone AN, Mackenzie PI, Galetin A, Houston JB, Miners JO. Stone AN, et al. Among authors: mackenzie pi. Drug Metab Dispos. 2003 Sep;31(9):1086-9. doi: 10.1124/dmd.31.9.1086. Drug Metab Dispos. 2003. PMID: 12920162

2

Drug glucuronidation in humans.

Miners JO, Mackenzie PI. Miners JO, et al. Among authors: mackenzie pi. Pharmacol Ther. 1991;51(3):347-69. doi: 10.1016/0163-7258(91)90065-t. Pharmacol Ther. 1991. PMID: 1792239 Review.

3

Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9.

Veronese ME, Mackenzie PI, Doecke CJ, McManus ME, Miners JO, Birkett DJ. Veronese ME, et al. Among authors: mackenzie pi. Biochem Biophys Res Commun. 1991 Mar 29;175(3):1112-8. doi: 10.1016/0006-291x(91)91680-b. Biochem Biophys Res Commun. 1991. PMID: 2025243

4

Expression of chimeric cDNAs in cell culture defines a region of UDP glucuronosyltransferase involved in substrate selection.

Mackenzie PI. Mackenzie PI. J Biol Chem. 1990 Feb 25;265(6):3432-5. J Biol Chem. 1990. PMID: 2105949 Free article.

5

The effect of N-linked glycosylation on the substrate preferences of UDP glucuronosyltransferases.

Mackenzie PI. Mackenzie PI. Biochem Biophys Res Commun. 1990 Feb 14;166(3):1293-9. doi: 10.1016/0006-291x(90)91006-e. Biochem Biophys Res Commun. 1990. PMID: 2106315

6

Characterization and regulation of rat liver UDP glucuronosyltransferases.

Mackenzie PI, Chowdhury NR, Chowdhury JR. Mackenzie PI, et al. Clin Exp Pharmacol Physiol. 1989 Jun;16(6):501-4. doi: 10.1111/j.1440-1681.1989.tb01595.x. Clin Exp Pharmacol Physiol. 1989. PMID: 2504523 Review.

7

In vitro approaches can predict human drug metabolism.

Bickett DJ, MacKenzie PI, Veronese ME, Miners JO. Bickett DJ, et al. Among authors: mackenzie pi. Trends Pharmacol Sci. 1993 Aug;14(8):292-4. doi: 10.1016/0165-6147(93)90043-j. Trends Pharmacol Sci. 1993. PMID: 8249146 Review. No abstract available.

8

The glucuronidation of hydroxylated metabolites of benzo[a]pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP-glucuronosyltransferases.

Jin CJ, Miners JO, Burchell B, Mackenzie PI. Jin CJ, et al. Among authors: mackenzie pi. Carcinogenesis. 1993 Dec;14(12):2637-9. doi: 10.1093/carcin/14.12.2637. Carcinogenesis. 1993. PMID: 8269638

9

cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily.

Jin CJ, Miners JO, Lillywhite KJ, Mackenzie PI. Jin CJ, et al. Among authors: mackenzie pi. Biochem Biophys Res Commun. 1993 Jul 15;194(1):496-503. doi: 10.1006/bbrc.1993.1847. Biochem Biophys Res Commun. 1993. PMID: 8333863

10

Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs.

Jin C, Miners JO, Lillywhite KJ, Mackenzie PI. Jin C, et al. Among authors: mackenzie pi. J Pharmacol Exp Ther. 1993 Jan;264(1):475-9. J Pharmacol Exp Ther. 1993. PMID: 8423545

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