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cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension.
Christensen AE, Selheim F, de Rooij J, Dremier S, Schwede F, Dao KK, Martinez A, Maenhaut C, Bos JL, Genieser HG, Døskeland SO. Christensen AE, et al. Among authors: doskeland so. J Biol Chem. 2003 Sep 12;278(37):35394-402. doi: 10.1074/jbc.M302179200. Epub 2003 Jun 20. J Biol Chem. 2003. PMID: 12819211 Free article.
Cyclic nucleotide analogs as probes of signaling pathways.
Poppe H, Rybalkin SD, Rehmann H, Hinds TR, Tang XB, Christensen AE, Schwede F, Genieser HG, Bos JL, Doskeland SO, Beavo JA, Butt E. Poppe H, et al. Among authors: doskeland so. Nat Methods. 2008 Apr;5(4):277-8. doi: 10.1038/nmeth0408-277. Nat Methods. 2008. PMID: 18376388 No abstract available.
Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.
Herfindal L, Krakstad C, Myhren L, Hagland H, Kopperud R, Teigen K, Schwede F, Kleppe R, Døskeland SO. Herfindal L, et al. Among authors: doskeland so. PLoS One. 2014 Apr 16;9(4):e94926. doi: 10.1371/journal.pone.0094926. eCollection 2014. PLoS One. 2014. PMID: 24740327 Free PMC article.
189 results