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Page 1
Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa.
Renau TE, Léger R, Filonova L, Flamme EM, Wang M, Yen R, Madsen D, Griffith D, Chamberland S, Dudley MN, Lee VJ, Lomovskaya O, Watkins WJ, Ohta T, Nakayama K, Ishida Y. Renau TE, et al. Among authors: madsen d. Bioorg Med Chem Lett. 2003 Aug 18;13(16):2755-8. doi: 10.1016/s0960-894x(03)00556-0. Bioorg Med Chem Lett. 2003. PMID: 12873508
The relationship between physicochemical properties, in vitro activity and pharmacokinetic profiles of analogues of diamine-containing efflux pump inhibitors.
Watkins WJ, Landaverry Y, Léger R, Litman R, Renau TE, Williams N, Yen R, Zhang JZ, Chamberland S, Madsen D, Griffith D, Tembe V, Huie K, Dudley MN. Watkins WJ, et al. Among authors: madsen d. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4241-4. doi: 10.1016/j.bmcl.2003.07.030. Bioorg Med Chem Lett. 2003. PMID: 14623009
Quinazolinone-based fungal efflux pump inhibitors. Part 1: Discovery of an (N-methylpiperazine)-containing derivative with activity in clinically relevant Candida spp.
Lemoine RC, Glinka TW, Watkins WJ, Cho A, Yang J, Iqbal N, Singh R, Madsen D, Lolans K, Lomovskaya O, Oza U, Dudley MN. Lemoine RC, et al. Among authors: madsen d. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5127-31. doi: 10.1016/j.bmcl.2004.07.070. Bioorg Med Chem Lett. 2004. PMID: 15380213
Quinazolinone fungal efflux pump inhibitors. Part 2: In vitro structure-activity relationships of (N-methyl-piperazinyl)-containing derivatives.
Watkins WJ, Lemoine RC, Chong L, Cho A, Renau TE, Kuo B, Wong V, Ludwikow M, Garizi N, Iqbal N, Barnard J, Jankowska R, Singh R, Madsen D, Lolans K, Lomovskaya O, Oza U, Dudley MN. Watkins WJ, et al. Among authors: madsen d. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5133-7. doi: 10.1016/j.bmcl.2004.07.071. Bioorg Med Chem Lett. 2004. PMID: 15380214
Quinazolinone fungal efflux pump inhibitors. Part 3: (N-methyl)piperazine variants and pharmacokinetic optimization.
Watkins WJ, Chong L, Cho A, Hilgenkamp R, Ludwikow M, Garizi N, Iqbal N, Barnard J, Singh R, Madsen D, Lolans K, Lomovskaya O, Oza U, Kumaraswamy P, Blecken A, Bai S, Loury DJ, Griffith DC, Dudley MN. Watkins WJ, et al. Among authors: madsen d. Bioorg Med Chem Lett. 2007 May 15;17(10):2802-6. doi: 10.1016/j.bmcl.2007.02.047. Epub 2007 Feb 27. Bioorg Med Chem Lett. 2007. PMID: 17350259
Plastic pollution: What have we done? What more can we do?
Yu H, Deng Z, Zahidi I, Fai CM, Liang D, Madsen DØ. Yu H, et al. Among authors: madsen do. Ecotoxicol Environ Saf. 2024 Nov 1;286:117164. doi: 10.1016/j.ecoenv.2024.117164. Epub 2024 Oct 12. Ecotoxicol Environ Saf. 2024. PMID: 39396399 Free article. No abstract available.
231 results