Ura M - Search Results

1

Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889.

Endo M, Miwa M, Eda H, Ura M, Tanimura H, Ishikawa T, Miyazaki-Nose T, Hattori K, Shimma N, Yamada-Okabe H, Ishitsuka H. Endo M, et al. Among authors: ura m. Int J Cancer. 2003 Sep 20;106(5):799-805. doi: 10.1002/ijc.11276. Int J Cancer. 2003. PMID: 12866042

2

Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine.

Hattori K, Kohchi Y, Oikawa N, Suda H, Ura M, Ishikawa T, Miwa M, Endoh M, Eda H, Tanimura H, Kawashima A, Horii I, Ishitsuka H, Shimma N. Hattori K, et al. Among authors: ura m. Bioorg Med Chem Lett. 2003 Mar 10;13(5):867-72. doi: 10.1016/s0960-894x(02)01082-x. Bioorg Med Chem Lett. 2003. PMID: 12617910

3

A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts.

Endo M, Miwa M, Ura M, Tanimura H, Taniguchi K, Miyazaki Y, Ohwada J, Tsukazaki M, Niizuma S, Murata T, Ozawa S, Suda H, Ogawa K, Nanba E, Nagao S, Shimma N, Yamada-Okabe H. Endo M, et al. Among authors: ura m. Cancer Chemother Pharmacol. 2010 Jan;65(2):363-71. doi: 10.1007/s00280-009-1042-5. Cancer Chemother Pharmacol. 2010. PMID: 19495753

4

Selective inhibition of spontaneous pulmonary metastasis of Lewis lung carcinoma by 5'-deoxy-5-fluorouridine.

Ishikawa T, Ura M, Yamamoto T, Tanaka Y, Ishitsuka H. Ishikawa T, et al. Among authors: ura m. Int J Cancer. 1995 May 16;61(4):516-21. doi: 10.1002/ijc.2910610415. Int J Cancer. 1995. PMID: 7759157

5

The antiproliferative activity of DMDC is modulated by inhibition of cytidine deaminase.

Eda H, Ura M, F-Ouchi K, Tanaka Y, Miwa M, Ishitsuka H. Eda H, et al. Among authors: ura m. Cancer Res. 1998 Mar 15;58(6):1165-9. Cancer Res. 1998. PMID: 9515801

6

High susceptibility of human cancer xenografts with higher levels of cytidine deaminase to a 2'-deoxycytidine antimetabolite, 2'-deoxy-2'-methylidenecytidine.

Miwa M, Eda H, Ura M, Ouchi KF, Keith DD, Foley LH, Ishitsuka H. Miwa M, et al. Among authors: ura m. Clin Cancer Res. 1998 Feb;4(2):493-7. Clin Cancer Res. 1998. PMID: 9516941

7

Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue.

Miwa M, Ura M, Nishida M, Sawada N, Ishikawa T, Mori K, Shimma N, Umeda I, Ishitsuka H. Miwa M, et al. Among authors: ura m. Eur J Cancer. 1998 Jul;34(8):1274-81. doi: 10.1016/s0959-8049(98)00058-6. Eur J Cancer. 1998. PMID: 9849491

8

Design and synthesis of novel prodrugs of 2'-deoxy-2'-methylidenecytidine activated by membrane dipeptidase overexpressed in tumor tissues.

Kohchi Y, Hattori K, Oikawa N, Mizuguchi E, Isshiki Y, Aso K, Yoshinari K, Shirai H, Miwa M, Inagaki Y, Ura M, Ogawa K, Okabe H, Ishitsuka H, Shimma N. Kohchi Y, et al. Among authors: ura m. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2241-5. doi: 10.1016/j.bmcl.2007.01.066. Epub 2007 Jan 27. Bioorg Med Chem Lett. 2007. PMID: 17306533

9

Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5'-deoxy-5-fluorouridine.

Eda H, Fujimoto K, Watanabe S, Ura M, Hino A, Tanaka Y, Wada K, Ishitsuka H. Eda H, et al. Among authors: ura m. Cancer Chemother Pharmacol. 1993;32(5):333-8. doi: 10.1007/BF00735915. Cancer Chemother Pharmacol. 1993. PMID: 8339382

10

The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, capecitabine.

Shimma N, Umeda I, Arasaki M, Murasaki C, Masubuchi K, Kohchi Y, Miwa M, Ura M, Sawada N, Tahara H, Kuruma I, Horii I, Ishitsuka H. Shimma N, et al. Among authors: ura m. Bioorg Med Chem. 2000 Jul;8(7):1697-706. doi: 10.1016/s0968-0896(00)00087-0. Bioorg Med Chem. 2000. PMID: 10976516

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