Brouillette WJ - Search Results

1

Tethered dimers as NAD synthetase inhibitors with antibacterial activity.

Velu SE, Cristofoli WA, Garcia GJ, Brouillette CG, Pierson MC, Luan CH, DeLucas LJ, Brouillette WJ. Velu SE, et al. Among authors: brouillette wj, brouillette cg. J Med Chem. 2003 Jul 17;46(15):3371-81. doi: 10.1021/jm030003x. J Med Chem. 2003. PMID: 12852767

2

Dimethyl sulfoxide at 2.5% (v/v) alters the structural cooperativity and unfolding mechanism of dimeric bacterial NAD+ synthetase.

Yang ZW, Tendian SW, Carson WM, Brouillette WJ, Delucas LJ, Brouillette CG. Yang ZW, et al. Among authors: brouillette wj, brouillette cg. Protein Sci. 2004 Mar;13(3):830-41. doi: 10.1110/ps.03330104. Protein Sci. 2004. PMID: 14978314 Free PMC article.

3

Tethered dimer inhibitors of NAD synthetase: parallel synthesis of an aryl-substituted SAR library.

Velu SE, Luan CH, Delucas LJ, Brouillette CG, Brouillette WJ. Velu SE, et al. Among authors: brouillette wj, brouillette cg. J Comb Chem. 2005 Nov-Dec;7(6):898-904. doi: 10.1021/cc050063j. J Comb Chem. 2005. PMID: 16283799

4

Antibacterial nicotinamide adenine dinucleotide synthetase inhibitors: amide- and ether-linked tethered dimers with alpha-amino acid end groups.

Velu SE, Mou L, Luan CH, Yang ZW, DeLucas LJ, Brouillette CG, Brouillette WJ. Velu SE, et al. Among authors: brouillette wj, brouillette cg. J Med Chem. 2007 May 31;50(11):2612-21. doi: 10.1021/jm061349l. Epub 2007 May 10. J Med Chem. 2007. PMID: 17489580

5

Virtual screening to identify lead inhibitors for bacterial NAD synthetase (NADs).

Moro WB, Yang Z, Kane TA, Brouillette CG, Brouillette WJ. Moro WB, et al. Among authors: brouillette wj. Bioorg Med Chem Lett. 2009 Apr 1;19(7):2001-5. doi: 10.1016/j.bmcl.2009.02.034. Epub 2009 Feb 12. Bioorg Med Chem Lett. 2009. PMID: 19249205 Free PMC article.

6

SAR studies for a new class of antibacterial NAD biosynthesis inhibitors.

Moro WB, Yang Z, Kane TA, Zhou Q, Harville S, Brouillette CG, Brouillette WJ. Moro WB, et al. Among authors: brouillette wj. J Comb Chem. 2009 Jul-Aug;11(4):617-25. doi: 10.1021/cc9000357. J Comb Chem. 2009. PMID: 19408950 Free PMC article.

7

Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD+ synthetase from Bacillus anthracis.

McDonald HM, Pruett PS, Deivanayagam C, Protasevich II, Carson WM, DeLucas LJ, Brouillette WJ, Brouillette CG. McDonald HM, et al. Among authors: brouillette wj, brouillette cg. Acta Crystallogr D Biol Crystallogr. 2007 Aug;63(Pt 8):891-905. doi: 10.1107/S0907444907029769. Epub 2007 Jul 17. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 17642516

8

Discovery and evaluation of nNa_v1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells.

Dutta S, Lopez Charcas O, Tanner S, Gradek F, Driffort V, Roger S, Selander K, Velu SE, Brouillette W. Dutta S, et al. Bioorg Med Chem. 2018 May 15;26(9):2428-2436. doi: 10.1016/j.bmc.2018.04.003. Epub 2018 Apr 3. Bioorg Med Chem. 2018. PMID: 29673714 Free PMC article.

9

Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents.

Brouillette WJ, Bajpai SN, Ali SM, Velu SE, Atigadda VR, Lommer BS, Finley JB, Luo M, Air GM. Brouillette WJ, et al. Bioorg Med Chem. 2003 Jul 3;11(13):2739-49. doi: 10.1016/s0968-0896(03)00271-2. Bioorg Med Chem. 2003. PMID: 12788348

10

Structure of nicotinic acid mononucleotide adenylyltransferase from Bacillus anthracis.

Lu S, Smith CD, Yang Z, Pruett PS, Nagy L, McCombs D, Delucas LJ, Brouillette WJ, Brouillette CG. Lu S, et al. Among authors: brouillette wj, brouillette cg. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Oct 1;64(Pt 10):893-8. doi: 10.1107/S1744309108029102. Epub 2008 Sep 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18931430 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

59 results

Search Page

Filters