Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100.
De Clercq E, Yamamoto N, Pauwels R, Balzarini J, Witvrouw M, De Vreese K, Debyser Z, Rosenwirth B, Peichl P, Datema R, et al.
De Clercq E, et al. Among authors: yamamoto n.
Antimicrob Agents Chemother. 1994 Apr;38(4):668-74. doi: 10.1128/AAC.38.4.668.
Antimicrob Agents Chemother. 1994.
PMID: 7913308
Free PMC article.
Bicyclams, in which the cyclam (1,4,8,11-tetraazacyclotetradecane) moieties are tethered via an aliphatic bridge (i.e., propylene, as in JM2763) are potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) (E. De Clercq, N. Yamam …
Bicyclams, in which the cyclam (1,4,8,11-tetraazacyclotetradecane) moieties are tethered via an aliphatic bridge (i.e., propylene, as in JM2 …