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Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100.
De Clercq E, Yamamoto N, Pauwels R, Balzarini J, Witvrouw M, De Vreese K, Debyser Z, Rosenwirth B, Peichl P, Datema R, et al. De Clercq E, et al. Among authors: yamamoto n. Antimicrob Agents Chemother. 1994 Apr;38(4):668-74. doi: 10.1128/AAC.38.4.668. Antimicrob Agents Chemother. 1994. PMID: 7913308 Free PMC article.
Bicyclams, in which the cyclam (1,4,8,11-tetraazacyclotetradecane) moieties are tethered via an aliphatic bridge (i.e., propylene, as in JM2763) are potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) (E. De Clercq, N. Yamam
Bicyclams, in which the cyclam (1,4,8,11-tetraazacyclotetradecane) moieties are tethered via an aliphatic bridge (i.e., propylene, as in JM2 …
Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event.
De Clercq E, Yamamoto N, Pauwels R, Baba M, Schols D, Nakashima H, Balzarini J, Debyser Z, Murrer BA, Schwartz D, et al. De Clercq E, et al. Among authors: yamamoto n. Proc Natl Acad Sci U S A. 1992 Jun 15;89(12):5286-90. doi: 10.1073/pnas.89.12.5286. Proc Natl Acad Sci U S A. 1992. PMID: 1608936 Free PMC article.
6,418 results