Gleason-Guzman M - Search Results

1

Design, synthesis, and evaluation of psorospermin/quinobenzoxazine hybrids as structurally novel antitumor agents.

Kim MY, Na Y, Vankayalapati H, Gleason-Guzman M, Hurley LH. Kim MY, et al. Among authors: gleason guzman m. J Med Chem. 2003 Jul 3;46(14):2958-72. doi: 10.1021/jm030096i. J Med Chem. 2003. PMID: 12825936

2

Conformationally restricted analogues of psorospermin: design, synthesis, and bioactivity of natural-product-related bisfuranoxanthones.

Heald RA, Dexheimer TS, Vankayalapati H, Siddiqui-Jain A, Szabo LZ, Gleason-Guzman MC, Hurley LH. Heald RA, et al. Among authors: gleason guzman mc. J Med Chem. 2005 Apr 21;48(8):2993-3004. doi: 10.1021/jm049299c. J Med Chem. 2005. PMID: 15828838

3

Design, synthesis, and biological evaluation of a series of fluoroquinoanthroxazines with contrasting dual mechanisms of action against topoisomerase II and G-quadruplexes.

Kim MY, Duan W, Gleason-Guzman M, Hurley LH. Kim MY, et al. Among authors: gleason guzman m. J Med Chem. 2003 Feb 13;46(4):571-83. doi: 10.1021/jm0203377. J Med Chem. 2003. PMID: 12570378

4

Psorospermin structural requirements for P-glycoprotein resistance reversal.

Carey SS, Gleason-Guzman M, Gokhale V, Hurley LH. Carey SS, et al. Among authors: gleason guzman m. Mol Cancer Ther. 2008 Nov;7(11):3617-23. doi: 10.1158/1535-7163.MCT-08-0519. Mol Cancer Ther. 2008. PMID: 19001443 Free PMC article.

5

The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures.

Kim MY, Gleason-Guzman M, Izbicka E, Nishioka D, Hurley LH. Kim MY, et al. Among authors: gleason guzman m. Cancer Res. 2003 Jun 15;63(12):3247-56. Cancer Res. 2003. PMID: 12810655

6

Determination of the importance of the stereochemistry of psorospermin in topoisomerase II-induced alkylation of DNA and in vitro and in vivo biological activity.

Fellows IM, Schwaebe M, Dexheimer TS, Vankayalapati H, Gleason-Guzman M, Whitten JP, Hurley LH. Fellows IM, et al. Among authors: gleason guzman m. Mol Cancer Ther. 2005 Nov;4(11):1729-39. doi: 10.1158/1535-7163.MCT-05-0183. Mol Cancer Ther. 2005. PMID: 16275994

7

Molecular cloning of the human platelet-derived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expression.

Qin Y, Fortin JS, Tye D, Gleason-Guzman M, Brooks TA, Hurley LH. Qin Y, et al. Among authors: gleason guzman m. Biochemistry. 2010 May 18;49(19):4208-19. doi: 10.1021/bi100330w. Biochemistry. 2010. PMID: 20377208 Free PMC article.

8

Mutations in the G-quadruplex silencer element and their relationship to c-MYC overexpression, NM23 repression, and therapeutic rescue.

Grand CL, Powell TJ, Nagle RB, Bearss DJ, Tye D, Gleason-Guzman M, Hurley LH. Grand CL, et al. Among authors: gleason guzman m. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6140-5. doi: 10.1073/pnas.0400460101. Epub 2004 Apr 12. Proc Natl Acad Sci U S A. 2004. Retraction in: Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):516. doi: 10.1073/pnas.0408999101. PMID: 15079086 Free PMC article. Retracted.

9

Mutations in the G-quadruplex silencer element and their relationship to c-MYC overexpression, NM23 repression, and therapeutic rescue.

Grand CL, Powell TJ, Nagle RB, Bearss DJ, Tye D, Gleason-Guzman M, Hurley LH. Grand CL, et al. Among authors: gleason guzman m. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):516. doi: 10.1073/pnas.0408999101. Proc Natl Acad Sci U S A. 2005. PMID: 15696627 Free PMC article. No abstract available.

10

Phase I pharmacokinetic trial and correlative in vitro phase II tumor kinetic study of Apomine (SR-45023A), a novel oral biphosphonate anticancer drug.

Alberts DS, Hallum AV 3rd, Stratton-Custis M, Garcia DJ, Gleason-Guzman M, Salmon SE, Santabarbara P, Niesor EJ, Floret S, Bentzen CL. Alberts DS, et al. Clin Cancer Res. 2001 May;7(5):1246-50. Clin Cancer Res. 2001. PMID: 11350890 Clinical Trial.

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