De Clercq E - Search Results

1

3'-C-branched 2'-deoxy-5-methyluridines: synthesis, enzyme inhibition, and antiviral properties.

Fedorov II, Kazmina EM, Novicov NA, Gurskaya GV, Bochkarev AV, Jasko MV, Victorova LS, Kukhanova MK, Balzarini J, De Clercq E, et al. Fedorov II, et al. Among authors: de clercq e. J Med Chem. 1992 Nov 27;35(24):4567-75. doi: 10.1021/jm00102a009. J Med Chem. 1992. PMID: 1281882

2

Novel 3'-C/N-substituted 2',3'-beta-D-dideoxynucleosides as potential chemotherapeutic agents. 1. Thymidine derivatives: synthesis, structure, and broad spectrum antiviral properties.

Fedorov II, Kazmina EM, Gurskaya GV, Jasko MV, Zavodnic VE, Balzarini J, De Clercq E, Faraj A, Sommadossi JP, Imbach JL, Gosselin G. Fedorov II, et al. Among authors: de clercq e. J Med Chem. 1997 Feb 14;40(4):486-94. doi: 10.1021/jm960500w. J Med Chem. 1997. PMID: 9046339

3

3'-(N-hydroxyimino)-2',3-dideoxynucleosides and their derivatives: synthesis, broad spectrum antiviral properties and synthetical application for the preparation of other nucleoside analogues.

Fedorov I, Kazmina E, Jasko M, Balzarini J, De Clercq E, Sommadossi JP, Imbach JL, Gosselin G. Fedorov I, et al. Among authors: de clercq e. Nucleosides Nucleotides. 1999 Apr-May;18(4-5):633-4. doi: 10.1080/15257779908041522. Nucleosides Nucleotides. 1999. PMID: 10432655

4

3'-Spiro nucleosides, a new class of specific human immunodeficiency virus type 1 inhibitors: synthesis and antiviral activity of [2'-5'-bis-O-(tert-butyldimethylsilyl)-beta-D-xylo- and -ribofuranose]-3'-spiro-5"-[4"-amino-1",2"-oxathiole 2",2"-dioxide] (TSAO) pyrimidine nucleosides.

Camarasa MJ, Pérez-Pérez MJ, San-Félix A, Balzarini J, De Clercq E. Camarasa MJ, et al. Among authors: de clercq e. J Med Chem. 1992 Jul 24;35(15):2721-7. doi: 10.1021/jm00093a002. J Med Chem. 1992. PMID: 1495006

5

Chemical modification of antibiotic streptonigrin; synthesis and properties of 2'-decarboxy-2'-aminostreptonigrin (streptonigrone-2'-imine).

Tolstikov VV, Preobrazhenskaya MN, Balzarini J, De Clercq E. Tolstikov VV, et al. Among authors: de clercq e. J Antibiot (Tokyo). 1992 Jun;45(6):1002-4. doi: 10.7164/antibiotics.45.1002. J Antibiot (Tokyo). 1992. PMID: 1500339 Free article. No abstract available.

6

3',3'-Difluoro-3'-deoxythymidine: comparison of anti-HIV activity to 3'-fluoro-3'-deoxythymidine.

Bergstrom DE, Mott AW, De Clercq E, Balzarini J, Swartling DJ. Bergstrom DE, et al. Among authors: de clercq e. J Med Chem. 1992 Sep 4;35(18):3369-72. doi: 10.1021/jm00096a011. J Med Chem. 1992. PMID: 1527788

7

5'-O-phosphonomethyl-2',3'-dideoxynucleosides: synthesis and anti-HIV activity.

Jie L, Van Aerschot A, Balzarini J, Janssen G, Busson R, Hoogmartens J, De Clercq E, Herdewijn P. Jie L, et al. Among authors: de clercq e. J Med Chem. 1990 Sep;33(9):2481-7. doi: 10.1021/jm00171a023. J Med Chem. 1990. PMID: 1697345

8

Synthesis and antiretrovirus properties of 5'-isocyano-5'-deoxythymidine, 5'-isocyano-2',5'-dideoxyuridine, 3'-azido-5'-isocyano-3',5'-dideoxythymidine, and 3'-azido-5'-isocyano-2',3',5'-trideoxyuridine.

Hiebl J, Zbiral E, Balzarini J, De Clercq E. Hiebl J, et al. Among authors: de clercq e. J Med Chem. 1991 Apr;34(4):1426-30. doi: 10.1021/jm00108a028. J Med Chem. 1991. PMID: 2016718

9

Synthesis and antiviral and cytostatic properties of 3'-deoxy-3'-fluoro- and 2'-azido-3'-fluoro-2',3'-dideoxy-D-ribofuranosides of natural heterocyclic bases.

Mikhailopulo IA, Poopeiko NE, Pricota TI, Sivets GG, Kvasyuk EI, Balzarini J, De Clercq E. Mikhailopulo IA, et al. Among authors: de clercq e. J Med Chem. 1991 Jul;34(7):2195-202. doi: 10.1021/jm00111a040. J Med Chem. 1991. PMID: 2066992

10

Synthesis, antiretrovirus effects, and phosphorylation kinetics of 3'-isocyano-3'-deoxythymidine and 3'-isocyano-2',3'-dideoxyuridine.

Hiebl J, Zbiral E, Balzarini J, De Clercq E. Hiebl J, et al. Among authors: de clercq e. J Med Chem. 1990 Feb;33(2):845-8. doi: 10.1021/jm00164a059. J Med Chem. 1990. PMID: 2299647

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