Southan GJ - Search Results

1

Potentiation of the vasorelaxant activity of nitric oxide by hydroxyguanidine: implications for the nature of endothelium-derived relaxing factor.

Zembowicz A, Swierkosz TA, Southan GJ, Hecker M, Vane JR. Zembowicz A, et al. Among authors: southan gj. Br J Pharmacol. 1992 Dec;107(4):1001-7. doi: 10.1111/j.1476-5381.1992.tb13398.x. Br J Pharmacol. 1992. PMID: 1281716 Free PMC article.

2

Mechanisms of the endothelium-dependent relaxation induced by NG-hydroxy-L-arginine.

Zembowicz A, Swierkosz TA, Southan GJ, Hecker M, Gryglewski RJ, Vane JR. Zembowicz A, et al. Among authors: southan gj. J Cardiovasc Pharmacol. 1992;20 Suppl 12:S57-9. doi: 10.1097/00005344-199204002-00017. J Cardiovasc Pharmacol. 1992. PMID: 1282987

3

Inhibition by spermine of the induction of nitric oxide synthase in J774.2 macrophages: requirement of a serum factor.

Szabó C, Southan GJ, Wood E, Thiemermann C, Vane JR. Szabó C, et al. Among authors: southan gj. Br J Pharmacol. 1994 Jun;112(2):355-6. doi: 10.1111/j.1476-5381.1994.tb13078.x. Br J Pharmacol. 1994. PMID: 7521253 Free PMC article.

4

The mechanism of the inhibitory effect of polyamines on the induction of nitric oxide synthase: role of aldehyde metabolites.

Szabó C, Southan GJ, Thiemermann C, Vane JR. Szabó C, et al. Among authors: southan gj. Br J Pharmacol. 1994 Nov;113(3):757-66. doi: 10.1111/j.1476-5381.1994.tb17058.x. Br J Pharmacol. 1994. PMID: 7532082 Free PMC article.

5

Characterization of serine protease-derived metabolites of big endothelin in the cytosolic fraction from human polymorphonuclear leukocytes.

Kaw S, Hecker M, Southan GJ, Warner TD, Vane JR. Kaw S, et al. Among authors: southan gj. J Cardiovasc Pharmacol. 1992;20 Suppl 12:S22-4. doi: 10.1097/00005344-199204002-00008. J Cardiovasc Pharmacol. 1992. PMID: 1282976

6

Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity.

Southan GJ, Szabó C, Thiemermann C. Southan GJ, et al. Br J Pharmacol. 1995 Jan;114(2):510-6. doi: 10.1111/j.1476-5381.1995.tb13256.x. Br J Pharmacol. 1995. PMID: 7533622 Free PMC article.

7

Attenuation of endotoxin-induced multiple organ dysfunction by 1-amino-2-hydroxy-guanidine, a potent inhibitor of inducible nitric oxide synthase.

Ruetten H, Southan GJ, Abate A, Thiemermann C. Ruetten H, et al. Among authors: southan gj. Br J Pharmacol. 1996 May;118(2):261-70. doi: 10.1111/j.1476-5381.1996.tb15397.x. Br J Pharmacol. 1996. PMID: 8735625 Free PMC article.

8

Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.

Szabó C, Southan GJ, Thiemermann C. Szabó C, et al. Among authors: southan gj. Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12472-6. doi: 10.1073/pnas.91.26.12472. Proc Natl Acad Sci U S A. 1994. PMID: 7528923 Free PMC article.

9

Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform.

Southan GJ, Zingarelli B, O'Connor M, Salzman AL, Szabó C. Southan GJ, et al. Br J Pharmacol. 1996 Feb;117(4):619-32. doi: 10.1111/j.1476-5381.1996.tb15236.x. Br J Pharmacol. 1996. PMID: 8646406 Free PMC article.

10

Inhibition of the induction of nitric oxide synthase by spermine is modulated by aldehyde dehydrogenase.

Southan GJ, Szabó C, Thiemermann C. Southan GJ, et al. Biochem Biophys Res Commun. 1994 Sep 30;203(3):1638-44. doi: 10.1006/bbrc.1994.2374. Biochem Biophys Res Commun. 1994. PMID: 7524490

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