Spiegelman B - Search Results

1

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.

Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC. Mootha VK, et al. Among authors: spiegelman b. Nat Genet. 2003 Jul;34(3):267-73. doi: 10.1038/ng1180. Nat Genet. 2003. PMID: 12808457

2

Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle.

Mootha VK, Handschin C, Arlow D, Xie X, St Pierre J, Sihag S, Yang W, Altshuler D, Puigserver P, Patterson N, Willy PJ, Schulman IG, Heyman RA, Lander ES, Spiegelman BM. Mootha VK, et al. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6570-5. doi: 10.1073/pnas.0401401101. Epub 2004 Apr 20. Proc Natl Acad Sci U S A. 2004. PMID: 15100410 Free PMC article.

3

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator.

Puigserver P, Spiegelman BM. Puigserver P, et al. Endocr Rev. 2003 Feb;24(1):78-90. doi: 10.1210/er.2002-0012. Endocr Rev. 2003. PMID: 12588810 Review.

4

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction.

Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D, Spiegelman BM. Puigserver P, et al. Nature. 2003 May 29;423(6939):550-5. doi: 10.1038/nature01667. Epub 2003 May 18. Nature. 2003. PMID: 12754525

5

PGC-1beta in the regulation of hepatic glucose and energy metabolism.

Lin J, Tarr PT, Yang R, Rhee J, Puigserver P, Newgard CB, Spiegelman BM. Lin J, et al. Among authors: spiegelman bm. J Biol Chem. 2003 Aug 15;278(33):30843-8. doi: 10.1074/jbc.M303643200. Epub 2003 Jun 13. J Biol Chem. 2003. PMID: 12807885 Free article.

6

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.

Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Rodgers JT, et al. Nature. 2005 Mar 3;434(7029):113-8. doi: 10.1038/nature03354. Nature. 2005. PMID: 15744310

7

Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk.

Handschin C, Choi CS, Chin S, Kim S, Kawamori D, Kurpad AJ, Neubauer N, Hu J, Mootha VK, Kim YB, Kulkarni RN, Shulman GI, Spiegelman BM. Handschin C, et al. J Clin Invest. 2007 Nov;117(11):3463-74. doi: 10.1172/JCI31785. J Clin Invest. 2007. PMID: 17932564 Free PMC article.

8

Regulation of adipogenesis and energy balance by PPARgamma and PGC-1.

Spiegelman BM, Puigserver P, Wu Z. Spiegelman BM, et al. Int J Obes Relat Metab Disord. 2000 Nov;24 Suppl 4:S8-10. doi: 10.1038/sj.ijo.0801492. Int J Obes Relat Metab Disord. 2000. PMID: 11126248 Review.

9

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1.

Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, Newgard CB, Spiegelman BM. Yoon JC, et al. Among authors: spiegelman bm. Nature. 2001 Sep 13;413(6852):131-8. doi: 10.1038/35093050. Nature. 2001. PMID: 11557972

10

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres.

Lin J, Wu H, Tarr PT, Zhang CY, Wu Z, Boss O, Michael LF, Puigserver P, Isotani E, Olson EN, Lowell BB, Bassel-Duby R, Spiegelman BM. Lin J, et al. Among authors: spiegelman bm. Nature. 2002 Aug 15;418(6899):797-801. doi: 10.1038/nature00904. Nature. 2002. PMID: 12181572

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