Czarny B - Search Results

1

Roles of the two active sites of somatic angiotensin-converting enzyme in the cleavage of angiotensin I and bradykinin: insights from selective inhibitors.

Georgiadis D, Beau F, Czarny B, Cotton J, Yiotakis A, Dive V. Georgiadis D, et al. Among authors: czarny b. Circ Res. 2003 Jul 25;93(2):148-54. doi: 10.1161/01.RES.0000081593.33848.FC. Epub 2003 Jun 12. Circ Res. 2003. PMID: 12805239

2

Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide.

Akif M, Schwager SL, Anthony CS, Czarny B, Beau F, Dive V, Sturrock ED, Acharya KR. Akif M, et al. Among authors: czarny b. Biochem J. 2011 May 15;436(1):53-9. doi: 10.1042/BJ20102123. Biochem J. 2011. PMID: 21352096 Free PMC article.

3

Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1' loop canonical conformation.

Devel L, Garcia S, Czarny B, Beau F, LaJeunesse E, Vera L, Georgiadis D, Stura E, Dive V. Devel L, et al. Among authors: czarny b. J Biol Chem. 2010 Nov 12;285(46):35900-9. doi: 10.1074/jbc.M110.139634. Epub 2010 Sep 3. J Biol Chem. 2010. PMID: 20817735 Free PMC article.

4

Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme.

Masuyer G, Akif M, Czarny B, Beau F, Schwager SL, Sturrock ED, Isaac RE, Dive V, Acharya KR. Masuyer G, et al. Among authors: czarny b. FEBS J. 2014 Feb;281(3):943-56. doi: 10.1111/febs.12660. Epub 2013 Dec 24. FEBS J. 2014. PMID: 24289879 Free PMC article.

5

Third generation of matrix metalloprotease inhibitors: Gain in selectivity by targeting the depth of the S1' cavity.

Devel L, Czarny B, Beau F, Georgiadis D, Stura E, Dive V. Devel L, et al. Among authors: czarny b. Biochimie. 2010 Nov;92(11):1501-8. doi: 10.1016/j.biochi.2010.07.017. Epub 2010 Aug 7. Biochimie. 2010. PMID: 20696203 Review.

6

A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E-knockout mice.

Johnson JL, Devel L, Czarny B, George SJ, Jackson CL, Rogakos V, Beau F, Yiotakis A, Newby AC, Dive V. Johnson JL, et al. Among authors: czarny b. Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):528-35. doi: 10.1161/ATVBAHA.110.219147. Epub 2011 Jan 6. Arterioscler Thromb Vasc Biol. 2011. PMID: 21212406 Free PMC article.

7

Detection of matrix metalloproteinase active forms in complex proteomes: evaluation of affinity versus photoaffinity capture.

Bregant S, Huillet C, Devel L, Dabert-Gay AS, Beau F, Thai R, Czarny B, Yiotakis A, Dive V. Bregant S, et al. Among authors: czarny b. J Proteome Res. 2009 May;8(5):2484-94. doi: 10.1021/pr801069c. J Proteome Res. 2009. PMID: 19271733

8

Halogen bonding controls selectivity of FRET substrate probes for MMP-9.

Tranchant I, Vera L, Czarny B, Amoura M, Cassar E, Beau F, Stura EA, Dive V. Tranchant I, et al. Among authors: czarny b. Chem Biol. 2014 Mar 20;21(3):408-13. doi: 10.1016/j.chembiol.2014.01.008. Epub 2014 Feb 27. Chem Biol. 2014. PMID: 24583051

9

Zinc-Metalloproteinase Inhibitors: Evaluation of the Complex Role Played by the Zinc-Binding Group on Potency and Selectivity.

Rouanet-Mehouas C, Czarny B, Beau F, Cassar-Lajeunesse E, Stura EA, Dive V, Devel L. Rouanet-Mehouas C, et al. Among authors: czarny b. J Med Chem. 2017 Jan 12;60(1):403-414. doi: 10.1021/acs.jmedchem.6b01420. Epub 2016 Dec 20. J Med Chem. 2017. PMID: 27996256

10

Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies.

Czarny B, Stura EA, Devel L, Vera L, Cassar-Lajeunesse E, Beau F, Calderone V, Fragai M, Luchinat C, Dive V. Czarny B, et al. J Med Chem. 2013 Feb 14;56(3):1149-59. doi: 10.1021/jm301574d. Epub 2013 Feb 5. J Med Chem. 2013. PMID: 23343195

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