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Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs.
Planells-Cases R, Lutter D, Guyader C, Gerhards NM, Ullrich F, Elger DA, Kucukosmanoglu A, Xu G, Voss FK, Reincke SM, Stauber T, Blomen VA, Vis DJ, Wessels LF, Brummelkamp TR, Borst P, Rottenberg S, Jentsch TJ. Planells-Cases R, et al. Among authors: brummelkamp tr. EMBO J. 2015 Dec 14;34(24):2993-3008. doi: 10.15252/embj.201592409. Epub 2015 Nov 3. EMBO J. 2015. PMID: 26530471 Free PMC article.
The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension.
Haarhuis JHI, van der Weide RH, Blomen VA, Yáñez-Cuna JO, Amendola M, van Ruiten MS, Krijger PHL, Teunissen H, Medema RH, van Steensel B, Brummelkamp TR, de Wit E, Rowland BD. Haarhuis JHI, et al. Cell. 2017 May 4;169(4):693-707.e14. doi: 10.1016/j.cell.2017.04.013. Cell. 2017. PMID: 28475897 Free PMC article.
DNA damage induces p53-independent apoptosis through ribosome stalling.
Boon NJ, Oliveira RA, Körner PR, Kochavi A, Mertens S, Malka Y, Voogd R, van der Horst SEM, Huismans MA, Smabers LP, Draper JM, Wessels LFA, Haahr P, Roodhart JML, Schumacher TNM, Snippert HJ, Agami R, Brummelkamp TR. Boon NJ, et al. Among authors: brummelkamp tr. Science. 2024 May 17;384(6697):785-792. doi: 10.1126/science.adh7950. Epub 2024 May 16. Science. 2024. PMID: 38753784
109 results