Linch DC - Search Results

1

Incidence and prognostic significance of C-MPL expression in acute myeloid leukemia.

Chelvatheebam S, Langabeer SE, Linch DC, Hills RK, Greenwell P. Chelvatheebam S, et al. Among authors: linch dc. Leuk Res. 2003 Sep;27(9):869-70. doi: 10.1016/s0145-2126(03)00016-x. Leuk Res. 2003. PMID: 12804647 No abstract available.

2

ASXL1 mutations are infrequent in young patients with primary acute myeloid leukemia and their detection has a limited role in therapeutic risk stratification.

El-Sharkawi D, Ali A, Evans CM, Hills RK, Burnett AK, Linch DC, Gale RE. El-Sharkawi D, et al. Among authors: linch dc. Leuk Lymphoma. 2014 Jun;55(6):1326-31. doi: 10.3109/10428194.2013.833332. Epub 2013 Oct 9. Leuk Lymphoma. 2014. PMID: 23952244

3

Additional impact of mutational genotype on prognostic determination in resistant and relapsed acute myeloid leukaemia.

Linch DC, Hills RK, Gilkes A, Burnett AK, Russell N, Gale RE. Linch DC, et al. Leuk Res. 2021 Sep;108:106553. doi: 10.1016/j.leukres.2021.106553. Epub 2021 Mar 2. Leuk Res. 2021. PMID: 33706968

4

Reported cryptic rearrangements of CBFbeta-MYH11 in acute myeloid leukaemia are not due to false priming of contaminating DNA.

Langabeer SE, Gale RE, Walker H, Linch DC. Langabeer SE, et al. Among authors: linch dc. Leukemia. 2000 May;14(5):944-5. doi: 10.1038/sj.leu.2401751. Leukemia. 2000. PMID: 10803531 No abstract available.

5

TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis.

Bowen D, Groves MJ, Burnett AK, Patel Y, Allen C, Green C, Gale RE, Hills R, Linch DC. Bowen D, et al. Among authors: linch dc. Leukemia. 2009 Jan;23(1):203-6. doi: 10.1038/leu.2008.173. Epub 2008 Jul 3. Leukemia. 2009. PMID: 18596741 No abstract available.

6

The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia.

Allen C, Hills RK, Lamb K, Evans C, Tinsley S, Sellar R, O'Brien M, Yin JL, Burnett AK, Linch DC, Gale RE. Allen C, et al. Among authors: linch dc. Leukemia. 2013 Sep;27(9):1891-901. doi: 10.1038/leu.2013.186. Epub 2013 Jun 20. Leukemia. 2013. PMID: 23783394

7

RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years.

Bowen DT, Frew ME, Hills R, Gale RE, Wheatley K, Groves MJ, Langabeer SE, Kottaridis PD, Moorman AV, Burnett AK, Linch DC. Bowen DT, et al. Among authors: linch dc. Blood. 2005 Sep 15;106(6):2113-9. doi: 10.1182/blood-2005-03-0867. Epub 2005 Jun 9. Blood. 2005. PMID: 15951308 Free article.

8

Conflicting data on the prognostic significance of FLT3/TKD mutations in acute myeloid leukemia might be related to the incidence of biallelic disease.

Mead AJ, Gale RE, Hills RK, Gupta M, Young BD, Burnett AK, Linch DC. Mead AJ, et al. Among authors: linch dc. Blood. 2008 Jul 15;112(2):444-5; author reply 445. doi: 10.1182/blood-2008-02-140392. Blood. 2008. PMID: 18606888 Free PMC article. No abstract available.

9

The prognostic significance of IDH1 mutations in younger adult patients with acute myeloid leukemia is dependent on FLT3/ITD status.

Green CL, Evans CM, Hills RK, Burnett AK, Linch DC, Gale RE. Green CL, et al. Among authors: linch dc. Blood. 2010 Oct 14;116(15):2779-82. doi: 10.1182/blood-2010-02-270926. Epub 2010 Jul 22. Blood. 2010. PMID: 20651067 Free article. Clinical Trial.

10

Transcription-mediated amplification and hybridisation protection assay to determine BCR-ABL transcript levels in patients with chronic myeloid leukaemia.

Langabeer SE, Gale RE, Harvey RC, Cook RW, Mackinnon S, Linch DC. Langabeer SE, et al. Among authors: linch dc. Leukemia. 2002 Mar;16(3):393-9. doi: 10.1038/sj.leu.2402392. Leukemia. 2002. PMID: 11896544

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