Burkey BF - Search Results

1

1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.

Villhauer EB, Brinkman JA, Naderi GB, Burkey BF, Dunning BE, Prasad K, Mangold BL, Russell ME, Hughes TE. Villhauer EB, et al. Among authors: burkey bf. J Med Chem. 2003 Jun 19;46(13):2774-89. doi: 10.1021/jm030091l. J Med Chem. 2003. PMID: 12801240

2

The DPP-4 inhibitor vildagliptin increases pancreatic beta cell mass in neonatal rats.

Duttaroy A, Voelker F, Merriam K, Zhang X, Ren X, Subramanian K, Hughes TE, Burkey BF. Duttaroy A, et al. Among authors: burkey bf. Eur J Pharmacol. 2011 Jan 15;650(2-3):703-7. doi: 10.1016/j.ejphar.2010.10.062. Epub 2010 Nov 9. Eur J Pharmacol. 2011. PMID: 21070766

3

Acute and chronic effects of the incretin enhancer vildagliptin in insulin-resistant rats.

Burkey BF, Li X, Bolognese L, Balkan B, Mone M, Russell M, Hughes TE, Wang PR. Burkey BF, et al. J Pharmacol Exp Ther. 2005 Nov;315(2):688-95. doi: 10.1124/jpet.105.087064. Epub 2005 Jul 18. J Pharmacol Exp Ther. 2005. PMID: 16027230

4

Beta-cell expression of a dominant-negative HNF-1alpha compromises the ability of inhibition of dipeptidyl peptidase-4 to elicit a long-term augmentation of insulin secretion in mice.

Ahrén B, Sörhede Winzell M, Burkey B, Hughes TE. Ahrén B, et al. Eur J Pharmacol. 2005 Oct 3;521(1-3):164-8. doi: 10.1016/j.ejphar.2005.08.019. Epub 2005 Sep 19. Eur J Pharmacol. 2005. PMID: 16171801

5

Pharmacological strategies for reduction of lipid availability.

Foley JE, Anderson RC, Bell PA, Burkey BF, Deems RO, de Souza C, Dunning BE. Foley JE, et al. Among authors: burkey bf. Ann N Y Acad Sci. 1997 Sep 20;827:231-45. doi: 10.1111/j.1749-6632.1997.tb51838.x. Ann N Y Acad Sci. 1997. PMID: 9329758 Review. No abstract available.

6

DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide.

Ahrén B, Winzell MS, Wierup N, Sundler F, Burkey B, Hughes TE. Ahrén B, et al. Regul Pept. 2007 Oct 4;143(1-3):97-103. doi: 10.1016/j.regpep.2007.03.008. Epub 2007 Apr 11. Regul Pept. 2007. PMID: 17482289

7

The effect of 1,3-diaryl-[1H]-pyrazole-4-acetamides on glucose utilization in ob/ob mice.

Bebernitz GR, Argentieri G, Battle B, Brennan C, Balkan B, Burkey BF, Eckhardt M, Gao J, Kapa P, Strohschein RJ, Schuster HF, Wilson M, Xu DD. Bebernitz GR, et al. Among authors: burkey bf. J Med Chem. 2001 Aug 2;44(16):2601-11. doi: 10.1021/jm010032c. J Med Chem. 2001. PMID: 11472214

8

Preclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061.

Burkey BF, Hoglen NC, Inskeep P, Wyman M, Hughes TE, Vath JE. Burkey BF, et al. J Pharmacol Exp Ther. 2018 May;365(2):301-313. doi: 10.1124/jpet.117.246272. Epub 2018 Feb 28. J Pharmacol Exp Ther. 2018. PMID: 29491038

9

Adverse effects of dipeptidyl peptidases 8 and 9 inhibition in rodents revisited.

Burkey BF, Hoffmann PK, Hassiepen U, Trappe J, Juedes M, Foley JE. Burkey BF, et al. Diabetes Obes Metab. 2008 Nov;10(11):1057-61. doi: 10.1111/j.1463-1326.2008.00860.x. Epub 2008 Apr 17. Diabetes Obes Metab. 2008. PMID: 18422675

10

Vascular origin of vildagliptin-induced skin effects in Cynomolgus monkeys: pathomechanistic role of peripheral sympathetic system and neuropeptide Y.

Hoffmann P, Bentley P, Sahota P, Schoenfeld H, Martin L, Longo L, Spaet R, Moulin P, Pantano S, Dubost V, Lapadula D, Burkey B, Kaushik V, Zhou W, Hayes M, Flavahan N, Chibout SD, Busch S. Hoffmann P, et al. Toxicol Pathol. 2014 Jun;42(4):684-95. doi: 10.1177/0192623313516828. Epub 2014 Jan 20. Toxicol Pathol. 2014. PMID: 24448599

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