Willson M - Search Results

1

Evidence for the two phosphate binding sites of an analogue of the thioacyl intermediate for the Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase-catalyzed reaction, from its crystal structure.

Castilho MS, Pavão F, Oliva G, Ladame S, Willson M, Périé J. Castilho MS, et al. Among authors: willson m. Biochemistry. 2003 Jun 17;42(23):7143-51. doi: 10.1021/bi0206107. Biochemistry. 2003. PMID: 12795610

2

Crystal structure of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase complexed with an analogue of 1,3-bisphospho-d-glyceric acid.

Ladame S, Castilho MS, Silva CH, Denier C, Hannaert V, Périé J, Oliva G, Willson M. Ladame S, et al. Among authors: willson m. Eur J Biochem. 2003 Nov;270(22):4574-86. doi: 10.1046/j.1432-1033.2003.03857.x. Eur J Biochem. 2003. PMID: 14622286 Free article.

3

Exploring the active site of Trypanosoma brucei phosphofructokinase by inhibition studies: specific irreversible inhibition.

Claustre S, Denier C, Lakhdar-Ghazal F, Lougare A, Lopez C, Chevalier N, Michels PA, Périé J, Willson M. Claustre S, et al. Among authors: willson m. Biochemistry. 2002 Aug 13;41(32):10183-93. doi: 10.1021/bi020082z. Biochemistry. 2002. PMID: 12162732

4

Selective inhibition of Trypanosoma cruzi GAPDH by "bi-substrate" analogues.

Ladame S, Fauré R, Denier C, Lakhdar-Ghazal F, Willson M. Ladame S, et al. Among authors: willson m. Org Biomol Chem. 2005 Jun 7;3(11):2070-2. doi: 10.1039/b504703j. Epub 2005 May 9. Org Biomol Chem. 2005. PMID: 15917890

5

Inhibition of glyceraldehyde-3-phosphate dehydrogenase by phosphorylated epoxides and alpha-enones.

Willson M, Lauth N, Perie J, Callens M, Opperdoes FR. Willson M, et al. Biochemistry. 1994 Jan 11;33(1):214-20. doi: 10.1021/bi00167a028. Biochemistry. 1994. PMID: 8286343

6

Selective inhibition of Trypanosoma brucei GAPDH by 1,3-bisphospho-D-glyceric acid (1,3-diPG) analogues.

Ladame S, Bardet M, Périé J, Willson M. Ladame S, et al. Among authors: willson m. Bioorg Med Chem. 2001 Mar;9(3):773-83. doi: 10.1016/s0968-0896(00)00295-9. Bioorg Med Chem. 2001. PMID: 11310612

7

Sequencing, modeling, and selective inhibition of Trypanosoma brucei hexokinase.

Willson M, Sanejouand YH, Perie J, Hannaert V, Opperdoes F. Willson M, et al. Chem Biol. 2002 Jul;9(7):839-47. doi: 10.1016/s1074-5521(02)00169-2. Chem Biol. 2002. PMID: 12144928

8

Glycolysis and proteases as targets for the design of new anti-trypanosome drugs.

Lakhdar-Ghazal F, Blonski C, Willson M, Michels P, Perie J. Lakhdar-Ghazal F, et al. Among authors: willson m. Curr Top Med Chem. 2002 May;2(5):439-56. doi: 10.2174/1568026024607472. Curr Top Med Chem. 2002. PMID: 11966466 Review.

9

[Rational concepts and the study of active molecules against various trypanosomiases].

Périé J, de Albuquerque C, Blonski C, Chauvière G, Gefflaut T, Page P, Trinquier M, Willson M. Périé J, et al. Among authors: willson m. Bull Soc Pathol Exot. 1994;87(5):353-61. Bull Soc Pathol Exot. 1994. PMID: 7496200 French.

10

Yeast hexokinase inhibitors designed from the 3-D enzyme structure rebuilding.

Willson M, Alric I, Perie J, Sanejouand YH. Willson M, et al. J Enzyme Inhib. 1997 Jun;12(2):101-21. doi: 10.3109/14756369709035812. J Enzyme Inhib. 1997. PMID: 9247853

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