D'Alessio G - Search Results

1

Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis.

Spalletti-Cernia D, Sorrentino R, Di Gaetano S, Arciello A, Garbi C, Piccoli R, D'Alessio G, Vecchio G, Laccetti P, Santoro M. Spalletti-Cernia D, et al. J Clin Endocrinol Metab. 2003 Jun;88(6):2900-7. doi: 10.1210/jc.2002-020373. J Clin Endocrinol Metab. 2003. PMID: 12788904

2

Highly selective toxic and proapoptotic effects of two dimeric ribonucleases on thyroid cancer cells compared to the effects of doxorubicin.

Spalletti-Cernia D, Sorrentino R, Di Gaetano S, Piccoli R, Santoro M, D'Alessio G, Laccetti P, Vecchio G. Spalletti-Cernia D, et al. Br J Cancer. 2004 Jan 12;90(1):270-7. doi: 10.1038/sj.bjc.6601491. Br J Cancer. 2004. PMID: 14710239 Free PMC article.

3

A fully human antitumor immunoRNase selective for ErbB-2-positive carcinomas.

De Lorenzo C, Arciello A, Cozzolino R, Palmer DB, Laccetti P, Piccoli R, D'Alessio G. De Lorenzo C, et al. Cancer Res. 2004 Jul 15;64(14):4870-4. doi: 10.1158/0008-5472.CAN-03-3717. Cancer Res. 2004. PMID: 15256457

4

A new RNase-based immunoconjugate selectively cytotoxic for ErbB2-overexpressing cells.

De Lorenzo C, Nigro A, Piccoli R, D'Alessio G. De Lorenzo C, et al. FEBS Lett. 2002 Apr 10;516(1-3):208-12. doi: 10.1016/s0014-5793(02)02527-9. FEBS Lett. 2002. PMID: 11959134 Free article.

5

A dimeric mutant of human pancreatic ribonuclease with selective cytotoxicity toward malignant cells.

Piccoli R, Di Gaetano S, De Lorenzo C, Grauso M, Monaco C, Spalletti-Cernia D, Laccetti P, Cinátl J, Matousek J, D'Alessio G. Piccoli R, et al. Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):7768-73. doi: 10.1073/pnas.96.14.7768. Proc Natl Acad Sci U S A. 1999. PMID: 10393896 Free PMC article.

6

Second generation antitumour human RNase: significance of its structural and functional features for the mechanism of antitumour action.

Di Gaetano S, D'alessio G, Piccoli R. Di Gaetano S, et al. Biochem J. 2001 Aug 15;358(Pt 1):241-7. doi: 10.1042/0264-6021:3580241. Biochem J. 2001. PMID: 11485573 Free PMC article.

7

In vivo and in vitro growth-inhibitory effect of bovine seminal ribonuclease on a system of rat thyroid epithelial transformed cells and tumors.

Laccetti P, Portella G, Mastronicola MR, Russo A, Piccoli R, D'Alessio G, Vecchio G. Laccetti P, et al. Cancer Res. 1992 Sep 1;52(17):4582-6. Cancer Res. 1992. PMID: 1511425

8

Seminal ribonuclease inhibits tumor growth and reduces the metastatic potential of Lewis lung carcinoma.

Laccetti P, Spalletti-Cernia D, Portella G, De Corato P, D'Alessio G, Vecchio G. Laccetti P, et al. Cancer Res. 1994 Aug 15;54(16):4253-6. Cancer Res. 1994. PMID: 8044766

9

A new human antitumor immunoreagent specific for ErbB2.

De Lorenzo C, Palmer DB, Piccoli R, Ritter MA, D'Alessio G. De Lorenzo C, et al. Clin Cancer Res. 2002 Jun;8(6):1710-9. Clin Cancer Res. 2002. PMID: 12060608

10

Key extracellular and intracellular steps in the antitumor action of seminal ribonuclease.

Mastronicola MR, Piccoli R, D'Alessio G. Mastronicola MR, et al. Eur J Biochem. 1995 May 15;230(1):242-9. doi: 10.1111/j.1432-1033.1995.tb20557.x. Eur J Biochem. 1995. PMID: 7601106 Free article.

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