Ryan AJ - Search Results

1

Tumour dose response to the antivascular agent ZD6126 assessed by magnetic resonance imaging.

Robinson SP, McIntyre DJ, Checkley D, Tessier JJ, Howe FA, Griffiths JR, Ashton SE, Ryan AJ, Blakey DC, Waterton JC. Robinson SP, et al. Among authors: ryan aj. Br J Cancer. 2003 May 19;88(10):1592-7. doi: 10.1038/sj.bjc.6600926. Br J Cancer. 2003. PMID: 12771928 Free PMC article.

2

Single dose of the antivascular agent, ZD6126 (N-acetylcolchinol-O-phosphate), reduces perfusion for at least 96 hours in the GH3 prolactinoma rat tumor model.

McIntyre DJ, Robinson SP, Howe FA, Griffiths JR, Ryan AJ, Blakey DC, Peers IS, Waterton JC. McIntyre DJ, et al. Among authors: ryan aj. Neoplasia. 2004 Mar-Apr;6(2):150-7. doi: 10.1593/neo.03247. Neoplasia. 2004. PMID: 15140404 Free PMC article.

3

Magnetic resonance imaging measurements of the response of murine and human tumors to the vascular-targeting agent ZD6126.

Evelhoch JL, LoRusso PM, He Z, DelProposto Z, Polin L, Corbett TH, Langmuir P, Wheeler C, Stone A, Leadbetter J, Ryan AJ, Blakey DC, Waterton JC. Evelhoch JL, et al. Among authors: ryan aj. Clin Cancer Res. 2004 Jun 1;10(11):3650-7. doi: 10.1158/1078-0432.CCR-03-0417. Clin Cancer Res. 2004. PMID: 15173071

4

Acute tumor response to ZD6126 assessed by intrinsic susceptibility magnetic resonance imaging.

Robinson SP, Kalber TL, Howe FA, McIntyre DJ, Griffiths JR, Blakey DC, Whittaker L, Ryan AJ, Waterton JC. Robinson SP, et al. Among authors: ryan aj. Neoplasia. 2005 May;7(5):466-74. doi: 10.1593/neo.04622. Neoplasia. 2005. PMID: 15967099 Free PMC article.

5

Tumour overexpression of inducible nitric oxide synthase (iNOS) increases angiogenesis and may modulate the anti-tumour effects of the vascular disrupting agent ZD6126.

Cullis ER, Kalber TL, Ashton SE, Cartwright JE, Griffiths JR, Ryan AJ, Robinson SP. Cullis ER, et al. Among authors: ryan aj. Microvasc Res. 2006 Mar;71(2):76-84. doi: 10.1016/j.mvr.2006.01.004. Epub 2006 Mar 10. Microvasc Res. 2006. PMID: 16530791

6

The response of RIF-1 fibrosarcomas to the vascular-disrupting agent ZD6126 assessed by in vivo and ex vivo 1H magnetic resonance spectroscopy.

Madhu B, Waterton JC, Griffiths JR, Ryan AJ, Robinson SP. Madhu B, et al. Among authors: ryan aj. Neoplasia. 2006 Jul;8(7):560-7. doi: 10.1593/neo.06319. Neoplasia. 2006. PMID: 16867218 Free PMC article.

7

Susceptibility contrast magnetic resonance imaging determination of fractional tumor blood volume: a noninvasive imaging biomarker of response to the vascular disrupting agent ZD6126.

Robinson SP, Howe FA, Griffiths JR, Ryan AJ, Waterton JC. Robinson SP, et al. Among authors: ryan aj. Int J Radiat Oncol Biol Phys. 2007 Nov 1;69(3):872-9. doi: 10.1016/j.ijrobp.2007.06.061. Int J Radiat Oncol Biol Phys. 2007. PMID: 17889267

8

Liposomal encapsulation enhances the antitumour efficacy of the vascular disrupting agent ZD6126 in murine B16.F10 melanoma.

Fens MH, Hill KJ, Issa J, Ashton SE, Westwood FR, Blakey DC, Storm G, Ryan AJ, Schiffelers RM. Fens MH, et al. Among authors: ryan aj. Br J Cancer. 2008 Oct 21;99(8):1256-64. doi: 10.1038/sj.bjc.6604675. Epub 2008 Sep 16. Br J Cancer. 2008. PMID: 18797467 Free PMC article.

9

False-negative MRI biomarkers of tumour response to targeted cancer therapeutics.

Boult JK, Jamin Y, Jacobs V, Gilmour LD, Walker-Samuel S, Halliday J, Elvin P, Ryan AJ, Waterton JC, Robinson SP. Boult JK, et al. Among authors: ryan aj. Br J Cancer. 2012 Jun 5;106(12):1960-6. doi: 10.1038/bjc.2012.208. Epub 2012 May 17. Br J Cancer. 2012. PMID: 22596237 Free PMC article.

10

Antitumor activity of the novel vascular targeting agent ZD6126 in a panel of tumor models.

Blakey DC, Westwood FR, Walker M, Hughes GD, Davis PD, Ashton SE, Ryan AJ. Blakey DC, et al. Among authors: ryan aj. Clin Cancer Res. 2002 Jun;8(6):1974-83. Clin Cancer Res. 2002. PMID: 12060643

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