Wong JC - Search Results

1

Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histone and tubulin acetylation.

Koeller KM, Haggarty SJ, Perkins BD, Leykin I, Wong JC, Kao MC, Schreiber SL. Koeller KM, et al. Among authors: wong jc. Chem Biol. 2003 May;10(5):397-410. doi: 10.1016/s1074-5521(03)00093-0. Chem Biol. 2003. PMID: 12770822

2

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation.

Haggarty SJ, Koeller KM, Wong JC, Grozinger CM, Schreiber SL. Haggarty SJ, et al. Among authors: wong jc. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4389-94. doi: 10.1073/pnas.0430973100. Epub 2003 Apr 3. Proc Natl Acad Sci U S A. 2003. PMID: 12677000 Free PMC article.

3

Structural biasing elements for in-cell histone deacetylase paralog selectivity.

Wong JC, Hong R, Schreiber SL. Wong JC, et al. J Am Chem Soc. 2003 May 14;125(19):5586-7. doi: 10.1021/ja0341440. J Am Chem Soc. 2003. PMID: 12733869

4

Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays.

Haggarty SJ, Koeller KM, Wong JC, Butcher RA, Schreiber SL. Haggarty SJ, et al. Among authors: wong jc. Chem Biol. 2003 May;10(5):383-96. doi: 10.1016/s1074-5521(03)00095-4. Chem Biol. 2003. PMID: 12770821

5

Modular synthesis and preliminary biological evaluation of stereochemically diverse 1,3-dioxanes.

Wong JC, Sternson SM, Louca JB, Hong R, Schreiber SL. Wong JC, et al. Chem Biol. 2004 Sep;11(9):1279-91. doi: 10.1016/j.chembiol.2004.07.012. Chem Biol. 2004. PMID: 15380188

6

Mapping chemical space using molecular descriptors and chemical genetics: deacetylase inhibitors.

Haggarty SJ, Clemons PA, Wong JC, Schreiber SL. Haggarty SJ, et al. Among authors: wong jc. Comb Chem High Throughput Screen. 2004 Nov;7(7):669-76. doi: 10.2174/1386207043328319. Comb Chem High Throughput Screen. 2004. PMID: 15578929 Review.

7

Synthesis of 7200 small molecules based on a substructural analysis of the histone deacetylase inhibitors trichostatin and trapoxin.

Sternson SM, Wong JC, Grozinger CM, Schreiber SL. Sternson SM, et al. Among authors: wong jc. Org Lett. 2001 Dec 27;3(26):4239-42. doi: 10.1021/ol016915f. Org Lett. 2001. PMID: 11784187

8

Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma.

Hideshima T, Bradner JE, Wong J, Chauhan D, Richardson P, Schreiber SL, Anderson KC. Hideshima T, et al. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8567-72. doi: 10.1073/pnas.0503221102. Epub 2005 Jun 3. Proc Natl Acad Sci U S A. 2005. PMID: 15937109 Free PMC article.

9

Split--pool synthesis of 1,3-dioxanes leading to arrayed stock solutions of single compounds sufficient for multiple phenotypic and protein-binding assays.

Sternson SM, Louca JB, Wong JC, Schreiber SL. Sternson SM, et al. Among authors: wong jc. J Am Chem Soc. 2001 Feb 28;123(8):1740-7. doi: 10.1021/ja0036108. J Am Chem Soc. 2001. PMID: 11456775

10

Melanocortin 1 receptor variants and skin cancer risk.

Han J, Kraft P, Colditz GA, Wong J, Hunter DJ. Han J, et al. Int J Cancer. 2006 Oct 15;119(8):1976-84. doi: 10.1002/ijc.22074. Int J Cancer. 2006. PMID: 16721784

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