Thummel KE - Search Results

1

CYP3A5 genotype predicts renal CYP3A activity and blood pressure in healthy adults.

Givens RC, Lin YS, Dowling AL, Thummel KE, Lamba JK, Schuetz EG, Stewart PW, Watkins PB. Givens RC, et al. Among authors: thummel ke. J Appl Physiol (1985). 2003 Sep;95(3):1297-300. doi: 10.1152/japplphysiol.00322.2003. Epub 2003 May 16. J Appl Physiol (1985). 2003. PMID: 12754175 Free article. Clinical Trial.

2

The erythromycin breath test predicts the clearance of midazolam.

Lown KS, Thummel KE, Benedict PE, Shen DD, Turgeon DK, Berent S, Watkins PB. Lown KS, et al. Among authors: thummel ke. Clin Pharmacol Ther. 1995 Jan;57(1):16-24. doi: 10.1016/0009-9236(95)90261-9. Clin Pharmacol Ther. 1995. PMID: 7828377 Free article.

3

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test.

Lown KS, Kolars JC, Thummel KE, Barnett JL, Kunze KL, Wrighton SA, Watkins PB. Lown KS, et al. Among authors: thummel ke. Drug Metab Dispos. 1994 Nov-Dec;22(6):947-55. Drug Metab Dispos. 1994. PMID: 7895614

4

Selective expression of CYP3A5 and not CYP3A4 in human blood.

Janardan SK, Lown KS, Schmiedlin-Ren P, Thummel KE, Watkins PB. Janardan SK, et al. Among authors: thummel ke. Pharmacogenetics. 1996 Oct;6(5):379-85. doi: 10.1097/00008571-199610000-00001. Pharmacogenetics. 1996. PMID: 8946469

5

Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.

Schmiedlin-Ren P, Thummel KE, Fisher JM, Paine MF, Lown KS, Watkins PB. Schmiedlin-Ren P, et al. Among authors: thummel ke. Mol Pharmacol. 1997 May;51(5):741-54. doi: 10.1124/mol.51.5.741. Mol Pharmacol. 1997. PMID: 9145912

6

First-pass midazolam metabolism catalyzed by 1alpha,25-dihydroxy vitamin D3-modified Caco-2 cell monolayers.

Fisher JM, Wrighton SA, Watkins PB, Schmiedlin-Ren P, Calamia JC, Shen DD, Kunze KL, Thummel KE. Fisher JM, et al. Among authors: thummel ke. J Pharmacol Exp Ther. 1999 May;289(2):1134-42. J Pharmacol Exp Ther. 1999. PMID: 10215697

7

Ethanol and production of the hepatotoxic metabolite of acetaminophen in healthy adults.

Thummel KE, Slattery JT, Ro H, Chien JY, Nelson SD, Lown KE, Watkins PB. Thummel KE, et al. Clin Pharmacol Ther. 2000 Jun;67(6):591-9. doi: 10.1067/mcp.2000.106574. Clin Pharmacol Ther. 2000. PMID: 10872641 Free article. Clinical Trial.

8

The human CYP3A subfamily: practical considerations.

Wrighton SA, Schuetz EG, Thummel KE, Shen DD, Korzekwa KR, Watkins PB. Wrighton SA, et al. Among authors: thummel ke. Drug Metab Rev. 2000 Aug-Nov;32(3-4):339-61. doi: 10.1081/dmr-100102338. Drug Metab Rev. 2000. PMID: 11139133 Review. No abstract available.

9

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression.

Kuehl P, Zhang J, Lin Y, Lamba J, Assem M, Schuetz J, Watkins PB, Daly A, Wrighton SA, Hall SD, Maurel P, Relling M, Brimer C, Yasuda K, Venkataramanan R, Strom S, Thummel K, Boguski MS, Schuetz E. Kuehl P, et al. Nat Genet. 2001 Apr;27(4):383-91. doi: 10.1038/86882. Nat Genet. 2001. PMID: 11279519

10

Induction of CYP3A4 by 1 alpha,25-dihydroxyvitamin D3 is human cell line-specific and is unlikely to involve pregnane X receptor.

Schmiedlin-Ren P, Thummel KE, Fisher JM, Paine MF, Watkins PB. Schmiedlin-Ren P, et al. Among authors: thummel ke. Drug Metab Dispos. 2001 Nov;29(11):1446-53. Drug Metab Dispos. 2001. PMID: 11602520

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