Zhang D - Search Results

1

A fragment of anthrax lethal factor delivers proteins to the cytosol without requiring protective antigen.

Kushner N, Zhang D, Touzjian N, Essex M, Lieberman J, Lu Y. Kushner N, et al. Among authors: zhang d. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6652-7. doi: 10.1073/pnas.1131930100. Epub 2003 May 9. Proc Natl Acad Sci U S A. 2003. PMID: 12740437 Free PMC article.

2

Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis.

Zhang D, Beresford PJ, Greenberg AH, Lieberman J. Zhang D, et al. Proc Natl Acad Sci U S A. 2001 May 8;98(10):5746-51. doi: 10.1073/pnas.101329598. Epub 2001 May 1. Proc Natl Acad Sci U S A. 2001. PMID: 11331782 Free PMC article.

3

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A.

Fan Z, Beresford PJ, Zhang D, Lieberman J. Fan Z, et al. Among authors: zhang d. Mol Cell Biol. 2002 Apr;22(8):2810-20. doi: 10.1128/MCB.22.8.2810-2820.2002. Mol Cell Biol. 2002. PMID: 11909973 Free PMC article.

4

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A.

Fan Z, Beresford PJ, Zhang D, Xu Z, Novina CD, Yoshida A, Pommier Y, Lieberman J. Fan Z, et al. Among authors: zhang d. Nat Immunol. 2003 Feb;4(2):145-53. doi: 10.1038/ni885. Epub 2003 Jan 13. Nat Immunol. 2003. PMID: 12524539

5

Granzyme B binds to target cells mostly by charge and must be added at the same time as perforin to trigger apoptosis.

Shi L, Keefe D, Durand E, Feng H, Zhang D, Lieberman J. Shi L, et al. Among authors: zhang d. J Immunol. 2005 May 1;174(9):5456-61. doi: 10.4049/jimmunol.174.9.5456. J Immunol. 2005. PMID: 15843543

6

Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor.

Fan Z, Beresford PJ, Oh DY, Zhang D, Lieberman J. Fan Z, et al. Among authors: zhang d. Cell. 2003 Mar 7;112(5):659-72. doi: 10.1016/s0092-8674(03)00150-8. Cell. 2003. PMID: 12628186 Free article.

7

Listeria-infected myeloid dendritic cells produce IFN-beta, priming T cell activation.

Feng H, Zhang D, Palliser D, Zhu P, Cai S, Schlesinger A, Maliszewski L, Lieberman J. Feng H, et al. Among authors: zhang d. J Immunol. 2005 Jul 1;175(1):421-32. doi: 10.4049/jimmunol.175.1.421. J Immunol. 2005. PMID: 15972676

8

The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5'-diphosphate-ribose) polymerase-1.

Zhu P, Martinvalet D, Chowdhury D, Zhang D, Schlesinger A, Lieberman J. Zhu P, et al. Among authors: zhang d. Blood. 2009 Aug 6;114(6):1205-16. doi: 10.1182/blood-2008-12-195768. Epub 2009 Jun 8. Blood. 2009. PMID: 19506301 Free PMC article.

9

Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic.

Zhang D, Shankar P, Xu Z, Harnisch B, Chen G, Lange C, Lee SJ, Valdez H, Lederman MM, Lieberman J. Zhang D, et al. Blood. 2003 Jan 1;101(1):226-35. doi: 10.1182/blood-2002-03-0791. Epub 2002 Aug 22. Blood. 2003. PMID: 12393740 Free article.

10

Granzyme A, which causes single-stranded DNA damage, targets the double-strand break repair protein Ku70.

Zhu P, Zhang D, Chowdhury D, Martinvalet D, Keefe D, Shi L, Lieberman J. Zhu P, et al. Among authors: zhang d. EMBO Rep. 2006 Apr;7(4):431-7. doi: 10.1038/sj.embor.7400622. Epub 2006 Jan 20. EMBO Rep. 2006. PMID: 16440001 Free PMC article.

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