Holman TR - Search Results

1

Kinetic investigations of the rate-limiting step in human 12- and 15-lipoxygenase.

Segraves EN, Holman TR. Segraves EN, et al. Among authors: holman tr. Biochemistry. 2003 May 13;42(18):5236-43. doi: 10.1021/bi0273462. Biochemistry. 2003. PMID: 12731864 Free article.

2

Oleyl sulfate reveals allosteric inhibition of soybean lipoxygenase-1 and human 15-lipoxygenase.

Mogul R, Johansen E, Holman TR. Mogul R, et al. Among authors: holman tr. Biochemistry. 2000 Apr 25;39(16):4801-7. doi: 10.1021/bi992805t. Biochemistry. 2000. PMID: 10769137 Free article.

3

Inhibition studies of soybean and human 15-lipoxygenases with long-chain alkenyl sulfate substrates.

Mogul R, Holman TR. Mogul R, et al. Among authors: holman tr. Biochemistry. 2001 Apr 10;40(14):4391-7. doi: 10.1021/bi002581a. Biochemistry. 2001. PMID: 11284695 Free article.

4

Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1.

Tomchick DR, Phan P, Cymborowski M, Minor W, Holman TR. Tomchick DR, et al. Among authors: holman tr. Biochemistry. 2001 Jun 26;40(25):7509-17. doi: 10.1021/bi002893d. Biochemistry. 2001. PMID: 11412104 Free article.

5

Probing sponge-derived terpenoids for human 15-lipoxygenase inhibitors.

Carroll J, Jonsson EN, Ebel R, Hartman MS, Holman TR, Crews P. Carroll J, et al. Among authors: holman tr. J Org Chem. 2001 Oct 19;66(21):6847-51. doi: 10.1021/jo015784t. J Org Chem. 2001. PMID: 11597201 Free article.

6

Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase.

Whitman S, Gezginci M, Timmermann BN, Holman TR. Whitman S, et al. Among authors: holman tr. J Med Chem. 2002 Jun 6;45(12):2659-61. doi: 10.1021/jm0201262. J Med Chem. 2002. PMID: 12036375 Free article.

7

Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.

Amagata T, Whitman S, Johnson TA, Stessman CC, Loo CP, Lobkovsky E, Clardy J, Crews P, Holman TR. Amagata T, et al. Among authors: holman tr. J Nat Prod. 2003 Feb;66(2):230-5. doi: 10.1021/np020462l. J Nat Prod. 2003. PMID: 12608855 Free article.

8

Stopped-flow kinetic investigations of the activation of soybean lipoxygenase-1 and the influence of inhibitors on the allosteric site.

Ruddat VC, Whitman S, Holman TR, Bernasconi CF. Ruddat VC, et al. Among authors: holman tr. Biochemistry. 2003 Apr 15;42(14):4172-8. doi: 10.1021/bi020698o. Biochemistry. 2003. PMID: 12680771 Free article.

9

Spectroscopic characterization of soybean lipoxygenase-1 mutants: the role of second coordination sphere residues in the regulation of enzyme activity.

Schenk G, Neidig ML, Zhou J, Holman TR, Solomon EI. Schenk G, et al. Among authors: holman tr. Biochemistry. 2003 Jun 24;42(24):7294-302. doi: 10.1021/bi027380g. Biochemistry. 2003. PMID: 12809485 Free article.

10

Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.

Segraves EN, Shah RR, Segraves NL, Johnson TA, Whitman S, Sui JK, Kenyon VA, Cichewicz RH, Crews P, Holman TR. Segraves EN, et al. Among authors: holman tr. J Med Chem. 2004 Jul 29;47(16):4060-5. doi: 10.1021/jm049872s. J Med Chem. 2004. PMID: 15267244 Free article.

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