Steiner DF - Search Results

1

Mutational analysis of predicted interactions between the catalytic and P domains of prohormone convertase 3 (PC3/PC1).

Ueda K, Lipkind GM, Zhou A, Zhu X, Kuznetsov A, Philipson L, Gardner P, Zhang C, Steiner DF. Ueda K, et al. Among authors: steiner df. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5622-7. doi: 10.1073/pnas.0631617100. Epub 2003 Apr 29. Proc Natl Acad Sci U S A. 2003. PMID: 12721373 Free PMC article.

2

Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3.

Zhu X, Orci L, Carroll R, Norrbom C, Ravazzola M, Steiner DF. Zhu X, et al. Among authors: steiner df. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10299-304. doi: 10.1073/pnas.162352799. Epub 2002 Jul 22. Proc Natl Acad Sci U S A. 2002. PMID: 12136131 Free PMC article.

3

Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects.

Zhu X, Zhou A, Dey A, Norrbom C, Carroll R, Zhang C, Laurent V, Lindberg I, Ugleholdt R, Holst JJ, Steiner DF. Zhu X, et al. Among authors: steiner df. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10293-8. doi: 10.1073/pnas.162352599. Epub 2002 Jul 26. Proc Natl Acad Sci U S A. 2002. PMID: 12145326 Free PMC article.

4

Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion.

Ma L, Bindokas VP, Kuznetsov A, Rhodes C, Hays L, Edwardson JM, Ueda K, Steiner DF, Philipson LH. Ma L, et al. Among authors: steiner df. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9266-71. doi: 10.1073/pnas.0403201101. Epub 2004 Jun 14. Proc Natl Acad Sci U S A. 2004. PMID: 15197259 Free PMC article.

5

Regulatory roles of the P domain of the subtilisin-like prohormone convertases.

Zhou A, Martin S, Lipkind G, LaMendola J, Steiner DF. Zhou A, et al. Among authors: steiner df. J Biol Chem. 1998 May 1;273(18):11107-14. doi: 10.1074/jbc.273.18.11107. J Biol Chem. 1998. PMID: 9556596 Free article.

6

A model for the structure of the P domains in the subtilisin-like prohormone convertases.

Lipkind GM, Zhou A, Steiner DF. Lipkind GM, et al. Among authors: steiner df. Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7310-5. doi: 10.1073/pnas.95.13.7310. Proc Natl Acad Sci U S A. 1998. PMID: 9636145 Free PMC article.

7

Predicted structural alterations in proinsulin during its interactions with prohormone convertases.

Lipkind G, Steiner DF. Lipkind G, et al. Among authors: steiner df. Biochemistry. 1999 Jan 19;38(3):890-6. doi: 10.1021/bi981556q. Biochemistry. 1999. PMID: 9893983

8

Furin and prohormone convertase 1/3 are major convertases in the processing of mouse pro-growth hormone-releasing hormone.

Dey A, Norrbom C, Zhu X, Stein J, Zhang C, Ueda K, Steiner DF. Dey A, et al. Among authors: steiner df. Endocrinology. 2004 Apr;145(4):1961-71. doi: 10.1210/en.2003-1472. Epub 2003 Dec 18. Endocrinology. 2004. PMID: 14684599

9

Significance of prohormone convertase 2, PC2, mediated initial cleavage at the proglucagon interdomain site, Lys70-Arg71, to generate glucagon.

Dey A, Lipkind GM, Rouillé Y, Norrbom C, Stein J, Zhang C, Carroll R, Steiner DF. Dey A, et al. Among authors: steiner df. Endocrinology. 2005 Feb;146(2):713-27. doi: 10.1210/en.2004-1118. Epub 2004 Nov 4. Endocrinology. 2005. PMID: 15528303

10

Pancreatic beta cells lack a low glucose and O2-inducible mitochondrial protein that augments cell survival.

Wang J, Cao Y, Chen Y, Chen Y, Gardner P, Steiner DF. Wang J, et al. Among authors: steiner df. Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10636-41. doi: 10.1073/pnas.0604194103. Epub 2006 Jun 30. Proc Natl Acad Sci U S A. 2006. PMID: 16815968 Free PMC article.

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