Williams MD - Search Results

1

Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis.

Bernard GR, Macias WL, Joyce DE, Williams MD, Bailey J, Vincent JL. Bernard GR, et al. Among authors: williams md. Crit Care. 2003 Apr;7(2):155-63. doi: 10.1186/cc2167. Epub 2003 Feb 28. Crit Care. 2003. PMID: 12720562 Free PMC article. Review.

2

Lack of evidence for qualitative treatment by disease severity interactions in clinical studies of severe sepsis.

Macias WL, Nelson DR, Williams M, Garg R, Janes J, Sashegyi A. Macias WL, et al. Crit Care. 2005;9(6):R607-22. doi: 10.1186/cc3795. Epub 2005 Sep 22. Crit Care. 2005. PMID: 16280057 Free PMC article. Review.

3

Drotrecogin alfa (activated) treatment of older patients with severe sepsis.

Ely EW, Angus DC, Williams MD, Bates B, Qualy R, Bernard GR. Ely EW, et al. Among authors: williams md. Clin Infect Dis. 2003 Jul 15;37(2):187-95. doi: 10.1086/375775. Epub 2003 Jul 8. Clin Infect Dis. 2003. PMID: 12856210 Clinical Trial.

4

New insights into the protein C pathway: potential implications for the biological activities of drotrecogin alfa (activated).

Macias WL, Yan SB, Williams MD, Um SL, Sandusky GE, Ballard DW, Planquois JM. Macias WL, et al. Among authors: williams md. Crit Care. 2005;9 Suppl 4(Suppl 4):S38-45. doi: 10.1186/cc3747. Epub 2005 Aug 25. Crit Care. 2005. PMID: 16168074 Free PMC article. Review.

5

Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial.

Nadel S, Goldstein B, Williams MD, Dalton H, Peters M, Macias WL, Abd-Allah SA, Levy H, Angle R, Wang D, Sundin DP, Giroir B; REsearching severe Sepsis and Organ dysfunction in children: a gLobal perspective (RESOLVE) study group. Nadel S, et al. Among authors: williams md. Lancet. 2007 Mar 10;369(9564):836-843. doi: 10.1016/S0140-6736(07)60411-5. Lancet. 2007. PMID: 17350452 Clinical Trial.

6

International integrated database for the evaluation of severe sepsis and drotrecogin alfa (activated) therapy: 28-day survival and safety.

Laterre PF, Nelson DR, Macias W, Abraham E, Sashegyi A, Williams MD, Levy M, Levi M, Utterback B, Vincent JL. Laterre PF, et al. Among authors: williams md. J Crit Care. 2007 Jun;22(2):142-52. doi: 10.1016/j.jcrc.2006.09.007. Epub 2007 Jan 31. J Crit Care. 2007. PMID: 17548026

7

Prophylactic heparin in patients with severe sepsis treated with drotrecogin alfa (activated).

Levi M, Levy M, Williams MD, Douglas I, Artigas A, Antonelli M, Wyncoll D, Janes J, Booth FV, Wang D, Sundin DP, Macias WL; Xigris and Prophylactic HepaRin Evaluation in Severe Sepsis (XPRESS) Study Group. Levi M, et al. Among authors: williams md. Am J Respir Crit Care Med. 2007 Sep 1;176(5):483-90. doi: 10.1164/rccm.200612-1803OC. Epub 2007 Jun 7. Am J Respir Crit Care Med. 2007. PMID: 17556722 Clinical Trial.

8

Influence of enrollment sequence effect on observed outcomes in the ADDRESS and PROWESS studies of drotrecogin alfa (activated) in patients with severe sepsis.

Laterre PF, Macias WL, Janes J, Williams MD, Nelson DR, Girbes AR, Dhainaut JF, Abraham E. Laterre PF, et al. Among authors: williams md. Crit Care. 2008;12(5):R117. doi: 10.1186/cc7011. Epub 2008 Sep 11. Crit Care. 2008. PMID: 18786266 Free PMC article.

9

Is worsening multiple organ failure the cause of death in patients with severe sepsis?

Vincent JL, Nelson DR, Williams MD. Vincent JL, et al. Among authors: williams md. Crit Care Med. 2011 May;39(5):1050-5. doi: 10.1097/CCM.0b013e31820eda29. Crit Care Med. 2011. PMID: 21317650

10

Systemic host responses in severe sepsis analyzed by causative microorganism and treatment effects of drotrecogin alfa (activated).

Opal SM, Garber GE, LaRosa SP, Maki DG, Freebairn RC, Kinasewitz GT, Dhainaut JF, Yan SB, Williams MD, Graham DE, Nelson DR, Levy H, Bernard GR. Opal SM, et al. Among authors: williams md. Clin Infect Dis. 2003 Jul 1;37(1):50-8. doi: 10.1086/375593. Epub 2003 Jun 24. Clin Infect Dis. 2003. PMID: 12830408 Clinical Trial.

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