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Optimization of P1-P3 groups in symmetric and asymmetric HIV-1 protease inhibitors.
Eur J Biochem. 2003 Apr;270(8):1746-58. doi: 10.1046/j.1432-1033.2003.03533.x.
Eur J Biochem. 2003.
PMID: 12694187
Free article.
Design and synthesis of new potent C2-symmetric HIV-1 protease inhibitors. Use of L-mannaric acid as a peptidomimetic scaffold.
Alterman M, Björsne M, Mühlman A, Classon B, Kvarnström I, Danielson H, Markgren PO, Nillroth U, Unge T, Hallberg A, Samuelsson B.
Alterman M, et al. Among authors: muhlman a.
J Med Chem. 1998 Sep 24;41(20):3782-92. doi: 10.1021/jm970777b.
J Med Chem. 1998.
PMID: 9748353
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Synthesis of potent C(2)-symmetric, diol-based hiv-1 protease inhibitors. Investigation of thioalkyl and thioaryl P1/P1' substituents.
Mühlman A, Classon B, Hallberg A, Samuelsson B.
Mühlman A, et al.
J Med Chem. 2001 Oct 11;44(21):3402-6. doi: 10.1021/jm0011169.
J Med Chem. 2001.
PMID: 11585445
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Synthesis of novel, potent, diol-based HIV-1 protease inhibitors via intermolecular pinacol homocoupling of (2S)-2-benzyloxymethyl-4-phenylbutanal.
Mühlman A, Lindberg J, Classon B, Unge T, Hallberg A, Samuelsson B.
Mühlman A, et al.
J Med Chem. 2001 Oct 11;44(21):3407-16. doi: 10.1021/jm0011171.
J Med Chem. 2001.
PMID: 11585446
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