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Page 1
Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease.
Tufi R, Gandhi S, de Castro IP, Lehmann S, Angelova PR, Dinsdale D, Deas E, Plun-Favreau H, Nicotera P, Abramov AY, Willis AE, Mallucci GR, Loh SH, Martins LM. Tufi R, et al. Among authors: deas e. Nat Cell Biol. 2014 Feb;16(2):157-66. doi: 10.1038/ncb2901. Epub 2014 Jan 19. Nat Cell Biol. 2014. PMID: 24441527 Free PMC article.
Direct observation of the interconversion of normal and toxic forms of α-synuclein.
Cremades N, Cohen SI, Deas E, Abramov AY, Chen AY, Orte A, Sandal M, Clarke RW, Dunne P, Aprile FA, Bertoncini CW, Wood NW, Knowles TP, Dobson CM, Klenerman D. Cremades N, et al. Among authors: deas e. Cell. 2012 May 25;149(5):1048-59. doi: 10.1016/j.cell.2012.03.037. Cell. 2012. PMID: 22632969 Free PMC article.
PINK1 function in health and disease.
Deas E, Plun-Favreau H, Wood NW. Deas E, et al. EMBO Mol Med. 2009 Jun;1(3):152-65. doi: 10.1002/emmm.200900024. EMBO Mol Med. 2009. PMID: 20049715 Free PMC article. Review.
Mitophagy and Parkinson's disease: the PINK1-parkin link.
Deas E, Wood NW, Plun-Favreau H. Deas E, et al. Biochim Biophys Acta. 2011 Apr;1813(4):623-33. doi: 10.1016/j.bbamcr.2010.08.007. Epub 2010 Aug 21. Biochim Biophys Acta. 2011. PMID: 20736035 Free PMC article. Review.
PINK1 cleavage at position A103 by the mitochondrial protease PARL.
Deas E, Plun-Favreau H, Gandhi S, Desmond H, Kjaer S, Loh SH, Renton AE, Harvey RJ, Whitworth AJ, Martins LM, Abramov AY, Wood NW. Deas E, et al. Hum Mol Genet. 2011 Mar 1;20(5):867-79. doi: 10.1093/hmg/ddq526. Epub 2010 Dec 6. Hum Mol Genet. 2011. PMID: 21138942 Free PMC article.
Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress.
Muqit MM, Abou-Sleiman PM, Saurin AT, Harvey K, Gandhi S, Deas E, Eaton S, Payne Smith MD, Venner K, Matilla A, Healy DG, Gilks WP, Lees AJ, Holton J, Revesz T, Parker PJ, Harvey RJ, Wood NW, Latchman DS. Muqit MM, et al. Among authors: deas e. J Neurochem. 2006 Jul;98(1):156-69. doi: 10.1111/j.1471-4159.2006.03845.x. J Neurochem. 2006. PMID: 16805805 Free article.
28 results