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Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry.
Tsamis F, Gavrilov S, Kajumo F, Seibert C, Kuhmann S, Ketas T, Trkola A, Palani A, Clader JW, Tagat JR, McCombie S, Baroudy B, Moore JP, Sakmar TP, Dragic T. Tsamis F, et al. Among authors: palani a. J Virol. 2003 May;77(9):5201-8. doi: 10.1128/jvi.77.9.5201-5208.2003. J Virol. 2003. PMID: 12692222 Free PMC article.
SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo.
Strizki JM, Xu S, Wagner NE, Wojcik L, Liu J, Hou Y, Endres M, Palani A, Shapiro S, Clader JW, Greenlee WJ, Tagat JR, McCombie S, Cox K, Fawzi AB, Chou CC, Pugliese-Sivo C, Davies L, Moreno ME, Ho DD, Trkola A, Stoddart CA, Moore JP, Reyes GR, Baroudy BM. Strizki JM, et al. Among authors: palani a. Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12718-23. doi: 10.1073/pnas.221375398. Epub 2001 Oct 16. Proc Natl Acad Sci U S A. 2001. PMID: 11606733 Free PMC article.
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor.
Ma X, Sloman DL, Duggal R, Anderson KD, Ballard JE, Bharathan I, Brynczka C, Gathiaka S, Henderson TJ, Lyons TW, Miller R, Munsell EV, Orth P, Otte RD, Palani A, Rankic DA, Robinson MR, Sather AC, Solban N, Song XS, Wen X, Xu Z, Yang Y, Yang R, Day PJ, Stoeck A, Bennett DJ, Han Y. Ma X, et al. Among authors: palani a. J Med Chem. 2024 Jul 11;67(13):11024-11052. doi: 10.1021/acs.jmedchem.4c00572. Epub 2024 Jun 26. J Med Chem. 2024. PMID: 38924388 Clinical Trial.
Role of an epidural in laparoscopic surgeries.
Sundaram SM, Narayanan S, Sethuraman RM, Palani A. Sundaram SM, et al. Among authors: palani a. J Anaesthesiol Clin Pharmacol. 2024 Apr-Jun;40(2):365. doi: 10.4103/joacp.joacp_329_22. Epub 2023 Apr 7. J Anaesthesiol Clin Pharmacol. 2024. PMID: 38919436 Free PMC article. No abstract available.
Sensitive bispecific chimeric T cell receptors for cancer therapy.
Simon S, Bugos G, Prins R, Rajan A, Palani A, Heyer K, Stevens A, Zeng L, Thompson K, Price JP, Kluesner MK, Jaeger-Ruckstuhl C, Shabaneh TB, Olson JM, Su X, Riddell SR. Simon S, et al. Among authors: palani a. Res Sq [Preprint]. 2024 Apr 22:rs.3.rs-4253777. doi: 10.21203/rs.3.rs-4253777/v1. Res Sq. 2024. PMID: 38746248 Free PMC article. Preprint.
100 results