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The biologically crucial C terminus of cholecystokinin and the non-peptide agonist SR-146,131 share a common binding site in the human CCK1 receptor. Evidence for a crucial role of Met-121 in the activation process.
Escrieut C, Gigoux V, Archer E, Verrier S, Maigret B, Behrendt R, Moroder L, Bignon E, Silvente-Poirot S, Pradayrol L, Fourmy D. Escrieut C, et al. Among authors: archer e. J Biol Chem. 2002 Mar 1;277(9):7546-55. doi: 10.1074/jbc.M108563200. Epub 2001 Nov 27. J Biol Chem. 2002. PMID: 11724786 Free article.
The G-protein-coupled CCK2 receptor associates with phospholipase Cgamma1.
Arnould M, Tassa A, Ferrand A, Archer E, Estève JP, Pénalba V, Portolan G, Escherich A, Moroder L, Fourmy D, Seva C, Dufresne M. Arnould M, et al. Among authors: archer e. FEBS Lett. 2004 Jun 18;568(1-3):89-93. doi: 10.1016/j.febslet.2004.05.012. FEBS Lett. 2004. PMID: 15196926 Free article.
240 results