Kelder A - Search Results

1

Identification of anti-repressor elements that confer high and stable protein production in mammalian cells.

Kwaks TH, Barnett P, Hemrika W, Siersma T, Sewalt RG, Satijn DP, Brons JF, van Blokland R, Kwakman P, Kruckeberg AL, Kelder A, Otte AP. Kwaks TH, et al. Among authors: kelder a. Nat Biotechnol. 2003 May;21(5):553-8. doi: 10.1038/nbt814. Epub 2003 Apr 7. Nat Biotechnol. 2003. PMID: 12679786

2

Targeting of a histone acetyltransferase domain to a promoter enhances protein expression levels in mammalian cells.

Kwaks TH, Sewalt RG, van Blokland R, Siersma TJ, Kasiem M, Kelder A, Otte AP. Kwaks TH, et al. Among authors: kelder a. J Biotechnol. 2005 Jan 12;115(1):35-46. doi: 10.1016/j.jbiotec.2004.07.012. J Biotechnol. 2005. PMID: 15607223

3

Identification of a small subpopulation of candidate leukemia-initiating cells in the side population of patients with acute myeloid leukemia.

Moshaver B, van Rhenen A, Kelder A, van der Pol M, Terwijn M, Bachas C, Westra AH, Ossenkoppele GJ, Zweegman S, Schuurhuis GJ. Moshaver B, et al. Among authors: kelder a. Stem Cells. 2008 Dec;26(12):3059-67. doi: 10.1634/stemcells.2007-0861. Stem Cells. 2008. PMID: 19096043

4

Aberrant marker expression patterns on the CD34+CD38- stem cell compartment in acute myeloid leukemia allows to distinguish the malignant from the normal stem cell compartment both at diagnosis and in remission.

van Rhenen A, Moshaver B, Kelder A, Feller N, Nieuwint AW, Zweegman S, Ossenkoppele GJ, Schuurhuis GJ. van Rhenen A, et al. Among authors: kelder a. Leukemia. 2007 Aug;21(8):1700-7. doi: 10.1038/sj.leu.2404754. Epub 2007 May 24. Leukemia. 2007. PMID: 17525725

5

A simple one-tube assay for immunophenotypical quantification of leukemic stem cells in acute myeloid leukemia.

Zeijlemaker W, Kelder A, Oussoren-Brockhoff YJ, Scholten WJ, Snel AN, Veldhuizen D, Cloos J, Ossenkoppele GJ, Schuurhuis GJ. Zeijlemaker W, et al. Among authors: kelder a. Leukemia. 2016 Feb;30(2):439-46. doi: 10.1038/leu.2015.252. Epub 2015 Sep 16. Leukemia. 2016. PMID: 26437777

6

High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival.

van Rhenen A, Feller N, Kelder A, Westra AH, Rombouts E, Zweegman S, van der Pol MA, Waisfisz Q, Ossenkoppele GJ, Schuurhuis GJ. van Rhenen A, et al. Among authors: kelder a. Clin Cancer Res. 2005 Sep 15;11(18):6520-7. doi: 10.1158/1078-0432.CCR-05-0468. Clin Cancer Res. 2005. PMID: 16166428 Free article.

7

The novel AML stem cell associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells.

van Rhenen A, van Dongen GA, Kelder A, Rombouts EJ, Feller N, Moshaver B, Stigter-van Walsum M, Zweegman S, Ossenkoppele GJ, Jan Schuurhuis G. van Rhenen A, et al. Among authors: kelder a. Blood. 2007 Oct 1;110(7):2659-66. doi: 10.1182/blood-2007-03-083048. Epub 2007 Jul 3. Blood. 2007. PMID: 17609428 Free article.

8

Positive selection for CD90 as a purging option in acute myeloid leukemia stem cell transplants.

Feller N, Kelder A, Westra G, Ossenkoppele GJ, Schuurhuis GJ. Feller N, et al. Among authors: kelder a. Cytometry B Clin Cytom. 2008 Jan;74(1):9-16. doi: 10.1002/cyto.b.20375. Cytometry B Clin Cytom. 2008. PMID: 18061946 Free article.

9

Interleukin-2 receptor alpha-chain (CD25) expression on leukaemic blasts is predictive for outcome and level of residual disease in AML.

Terwijn M, Feller N, van Rhenen A, Kelder A, Westra G, Zweegman S, Ossenkoppele G, Schuurhuis GJ. Terwijn M, et al. Among authors: kelder a. Eur J Cancer. 2009 Jun;45(9):1692-9. doi: 10.1016/j.ejca.2009.02.021. Epub 2009 Mar 25. Eur J Cancer. 2009. PMID: 19321337

10

Normal hematopoietic stem cells within the AML bone marrow have a distinct and higher ALDH activity level than co-existing leukemic stem cells.

Schuurhuis GJ, Meel MH, Wouters F, Min LA, Terwijn M, de Jonge NA, Kelder A, Snel AN, Zweegman S, Ossenkoppele GJ, Smit L. Schuurhuis GJ, et al. Among authors: kelder a. PLoS One. 2013 Nov 11;8(11):e78897. doi: 10.1371/journal.pone.0078897. eCollection 2013. PLoS One. 2013. PMID: 24244383 Free PMC article. Clinical Trial.

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