Cowart M - Search Results

1

Synthesis and structure-activity relationships of 5-heteroatom-substituted pyridopyrimidines as adenosine kinase inhibitors.

Gfesser GA, Bayburt EK, Cowart M, DiDomenico S, Gomtsyan A, Lee CH, Stewart AO, Jarvis MF, Kowaluk EA, Bhagwat SS. Gfesser GA, et al. Among authors: cowart m. Eur J Med Chem. 2003 Mar;38(3):245-52. doi: 10.1016/s0223-5234(03)00019-9. Eur J Med Chem. 2003. PMID: 12667691

2

Adenosine kinase inhibitors: polar 7-substitutent of pyridopyrimidine derivatives improving their locomotor selectivity.

Zheng GZ, Mao Y, Lee CH, Pratt JK, Koenig JR, Perner RJ, Cowart MD, Gfesser GA, McGaraughty S, Chu KL, Zhu C, Yu H, Kohlhaas K, Alexander KM, Wismer CT, Mikusa J, Jarvis MF, Kowaluk EA, Stewart AO. Zheng GZ, et al. Among authors: cowart md. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3041-4. doi: 10.1016/s0960-894x(03)00642-5. Bioorg Med Chem Lett. 2003. PMID: 12941329

3

5-(3-Bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-ylamine: structure-activity relationships of 7-substituted heteroaryl analogs as non-nucleoside adenosine kinase inhibitors.

Matulenko MA, Lee CH, Jiang M, Frey RR, Cowart MD, Bayburt EK, Didomenico S, Gfesser GA, Gomtsyan A, Zheng GZ, McKie JA, Stewart AO, Yu H, Kohlhaas KL, Alexander KM, McGaraughty S, Wismer CT, Mikusa J, Marsh KC, Snyder RD, Diehl MS, Kowaluk EA, Jarvis MF, Bhagwat SS. Matulenko MA, et al. Among authors: cowart md. Bioorg Med Chem. 2005 Jun 1;13(11):3705-20. doi: 10.1016/j.bmc.2005.03.023. Bioorg Med Chem. 2005. PMID: 15863000

4

Structure-activity relationships of arylbenzofuran H3 receptor antagonists.

Gfesser GA, Faghih R, Bennani YL, Curtis MP, Esbenshade TA, Hancock AA, Cowart MD. Gfesser GA, et al. Bioorg Med Chem Lett. 2005 May 16;15(10):2559-63. doi: 10.1016/j.bmcl.2005.03.047. Bioorg Med Chem Lett. 2005. PMID: 15863316

5

Crystal structures of human adenosine kinase inhibitor complexes reveal two distinct binding modes.

Muchmore SW, Smith RA, Stewart AO, Cowart MD, Gomtsyan A, Matulenko MA, Yu H, Severin JM, Bhagwat SS, Lee CH, Kowaluk EA, Jarvis MF, Jakob CL. Muchmore SW, et al. Among authors: cowart md. J Med Chem. 2006 Nov 16;49(23):6726-31. doi: 10.1021/jm060189a. J Med Chem. 2006. PMID: 17154503

6

Analgesic and anti-inflammatory effects of A-286501, a novel orally active adenosine kinase inhibitor.

Jarvis MF, Yu H, McGaraughty S, Wismer CT, Mikusa J, Zhu C, Chu K, Kohlhaas K, Cowart M, Lee CH, Stewart AO, Cox BF, Polakowski J, Kowaluk EA. Jarvis MF, et al. Among authors: cowart m. Pain. 2002 Mar;96(1-2):107-18. doi: 10.1016/s0304-3959(01)00435-3. Pain. 2002. PMID: 11932067

7

Anticonvulsant and antinociceptive actions of novel adenosine kinase inhibitors.

McGaraughty S, Cowart M, Jarvis MF, Berman RF. McGaraughty S, et al. Among authors: cowart m. Curr Top Med Chem. 2005;5(1):43-58. doi: 10.2174/1568026053386845. Curr Top Med Chem. 2005. PMID: 15638777 Review.

8

Synthesis and SAR of 5-amino- and 5-(aminomethyl)benzofuran histamine H3 receptor antagonists with improved potency.

Sun M, Zhao C, Gfesser GA, Thiffault C, Miller TR, Marsh K, Wetter J, Curtis M, Faghih R, Esbenshade TA, Hancock AA, Cowart M. Sun M, et al. Among authors: cowart m. J Med Chem. 2005 Oct 6;48(20):6482-90. doi: 10.1021/jm0504398. J Med Chem. 2005. PMID: 16190774

9

Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase.

Cowart M, Kowaluk EA, Daanen JF, Kohlhaas KL, Alexander KM, Wagenaar FL, Kerwin JF Jr. Cowart M, et al. J Med Chem. 1998 Jul 2;41(14):2636-42. doi: 10.1021/jm980073h. J Med Chem. 1998. PMID: 9651169

10

Design of adenosine kinase inhibitors from the NMR-based screening of fragments.

Hajduk PJ, Gomtsyan A, Didomenico S, Cowart M, Bayburt EK, Solomon L, Severin J, Smith R, Walter K, Holzman TF, Stewart A, McGaraughty S, Jarvis MF, Kowaluk EA, Fesik SW. Hajduk PJ, et al. Among authors: cowart m. J Med Chem. 2000 Dec 14;43(25):4781-6. doi: 10.1021/jm000373a. J Med Chem. 2000. PMID: 11123986

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

160 results

Search Page

Filters