Isacson O - Search Results

1

Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome.

Hunter CL, Isacson O, Nelson M, Bimonte-Nelson H, Seo H, Lin L, Ford K, Kindy MS, Granholm AC. Hunter CL, et al. Among authors: isacson o. Neurosci Res. 2003 Apr;45(4):437-45. doi: 10.1016/s0168-0102(03)00005-1. Neurosci Res. 2003. PMID: 12657457

2

Spatial memory testing decreases hippocampal amyloid precursor protein in young, but not aged, female rats.

Bimonte HA, Granholm AC, Seo H, Isacson O. Bimonte HA, et al. Among authors: isacson o. Neurosci Lett. 2002 Aug 2;328(1):50-4. doi: 10.1016/s0304-3940(02)00442-1. Neurosci Lett. 2002. PMID: 12123857

3

Estrogen alters amyloid precursor protein as well as dendritic and cholinergic markers in a mouse model of Down syndrome.

Granholm AC, Sanders L, Seo H, Lin L, Ford K, Isacson O. Granholm AC, et al. Among authors: isacson o. Hippocampus. 2003;13(8):905-14. doi: 10.1002/hipo.10130. Hippocampus. 2003. PMID: 14750653

4

Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice.

Seo H, Isacson O. Seo H, et al. Among authors: isacson o. Exp Neurol. 2005 Jun;193(2):469-80. doi: 10.1016/j.expneurol.2004.11.017. Exp Neurol. 2005. PMID: 15869949

5

The hAPP-YAC transgenic model has elevated UPS activity in the frontal cortex similar to Alzheimer's disease and Down's syndrome.

Seo H, Isacson O. Seo H, et al. Among authors: isacson o. J Neurochem. 2010 Sep;114(6):1819-26. doi: 10.1111/j.1471-4159.2010.06902.x. Epub 2010 Aug 3. J Neurochem. 2010. PMID: 20698932 Free article.

6

Alzheimer's disease and Down's syndrome: roles of APP, trophic factors and ACh.

Isacson O, Seo H, Lin L, Albeck D, Granholm AC. Isacson O, et al. Trends Neurosci. 2002 Feb;25(2):79-84. doi: 10.1016/s0166-2236(02)02037-4. Trends Neurosci. 2002. PMID: 11814559 Review.

7

Cortico-hippocampal APP and NGF levels are dynamically altered by cholinergic muscarinic antagonist or M1 agonist treatment in normal mice.

Seo H, Ferree AW, Isacson O. Seo H, et al. Among authors: isacson o. Eur J Neurosci. 2002 Feb;15(3):498-506. doi: 10.1046/j.0953-816x.2001.01884.x. Eur J Neurosci. 2002. PMID: 11876777

8

Cholinergic modulation of amyloid processing and dementia in animal models of Alzheimer's disease.

Isacson O, Lin L. Isacson O, et al. Ann N Y Acad Sci. 2000;920:309-14. doi: 10.1111/j.1749-6632.2000.tb06940.x. Ann N Y Acad Sci. 2000. PMID: 11193169 Review. No abstract available.

9

Chronic cognitive deficits and amyloid precursor protein elevation after selective immunotoxin lesions of the basal forebrain cholinergic system.

Lin L, LeBlanc CJ, Deacon TW, Isacson O. Lin L, et al. Among authors: isacson o. Neuroreport. 1998 Feb 16;9(3):547-52. doi: 10.1097/00001756-199802160-00030. Neuroreport. 1998. PMID: 9512404

10

Gene therapy by proteasome activator, PA28γ, improves motor coordination and proteasome function in Huntington's disease YAC128 mice.

Jeon J, Kim W, Jang J, Isacson O, Seo H. Jeon J, et al. Among authors: isacson o. Neuroscience. 2016 Jun 2;324:20-8. doi: 10.1016/j.neuroscience.2016.02.054. Epub 2016 Mar 2. Neuroscience. 2016. PMID: 26944602

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