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Further exploration of 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]piperazine (GBR 12909): role of N-aromatic, N-heteroaromatic, and 3-oxygenated N-phenylpropyl substituents on affinity for the dopamine and serotonin transporter.
Lewis D, Zhang Y, Prisinzano T, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Lewis D, et al. Among authors: rothman rb. Bioorg Med Chem Lett. 2003 Apr 7;13(7):1385-9. doi: 10.1016/s0960-894x(03)00108-2. Bioorg Med Chem Lett. 2003. PMID: 12657288
Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine.
Hsin LW, Dersch CM, Baumann MH, Stafford D, Glowa JR, Rothman RB, Jacobson AE, Rice KC. Hsin LW, et al. Among authors: rothman rb. J Med Chem. 2002 Mar 14;45(6):1321-9. doi: 10.1021/jm010430f. J Med Chem. 2002. PMID: 11882001
Diaryldimethylpiperazine ligands with mu- and delta-opioid receptor affinity: Synthesis of (+)-4-[(alphaR)-alpha-(4-allyl-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl]-N-ethyl-N-phenylbenzamide and (-)-4-[(alphaR)-alpha-(2S,5S)-dimethylpiperazin-1-yl)-(3-hydroxyphenyl)methyl]-N-ethyl-N-phenylbenzamide.
Kim IJ, Ullrich T, Janetka JW, Furness MS, Jacobson AE, Rothman RB, Dersch CM, Flippen-Anderson JL, George C, Rice KC. Kim IJ, et al. Among authors: rothman rb. Bioorg Med Chem. 2003 Nov 3;11(22):4761-8. doi: 10.1016/s0968-0896(03)00496-6. Bioorg Med Chem. 2003. PMID: 14556791
421 results