Dover LG - Search Results

1

Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria.

Kremer L, Dover LG, Morbidoni HR, Vilchèze C, Maughan WN, Baulard A, Tu SC, Honoré N, Deretic V, Sacchettini JC, Locht C, Jacobs WR Jr, Besra GS. Kremer L, et al. Among authors: dover lg. J Biol Chem. 2003 Jun 6;278(23):20547-54. doi: 10.1074/jbc.M302435200. Epub 2003 Mar 24. J Biol Chem. 2003. PMID: 12654922 Free article.

2

Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis.

Kremer L, Douglas JD, Baulard AR, Morehouse C, Guy MR, Alland D, Dover LG, Lakey JH, Jacobs WR Jr, Brennan PJ, Minnikin DE, Besra GS. Kremer L, et al. Among authors: dover lg. J Biol Chem. 2000 Jun 2;275(22):16857-64. doi: 10.1074/jbc.M000569200. J Biol Chem. 2000. PMID: 10747933 Free article.

3

Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II.

Kremer L, Nampoothiri KM, Lesjean S, Dover LG, Graham S, Betts J, Brennan PJ, Minnikin DE, Locht C, Besra GS. Kremer L, et al. Among authors: dover lg. J Biol Chem. 2001 Jul 27;276(30):27967-74. doi: 10.1074/jbc.M103687200. Epub 2001 May 23. J Biol Chem. 2001. PMID: 11373295 Free article.

4

Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity.

Brown AK, Sridharan S, Kremer L, Lindenberg S, Dover LG, Sacchettini JC, Besra GS. Brown AK, et al. Among authors: dover lg. J Biol Chem. 2005 Sep 16;280(37):32539-47. doi: 10.1074/jbc.M413216200. Epub 2005 Jul 22. J Biol Chem. 2005. PMID: 16040614 Free article.

5

Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria.

Alahari A, Trivelli X, Guérardel Y, Dover LG, Besra GS, Sacchettini JC, Reynolds RC, Coxon GD, Kremer L. Alahari A, et al. Among authors: dover lg. PLoS One. 2007 Dec 19;2(12):e1343. doi: 10.1371/journal.pone.0001343. PLoS One. 2007. PMID: 18094751 Free PMC article.

6

The M. tuberculosis antigen 85 complex and mycolyltransferase activity.

Kremer L, Maughan WN, Wilson RA, Dover LG, Besra GS. Kremer L, et al. Among authors: dover lg. Lett Appl Microbiol. 2002;34(4):233-7. doi: 10.1046/j.1472-765x.2002.01091.x. Lett Appl Microbiol. 2002. PMID: 11940150

7

The methyl-branched fortifications of Mycobacterium tuberculosis.

Minnikin DE, Kremer L, Dover LG, Besra GS. Minnikin DE, et al. Among authors: dover lg. Chem Biol. 2002 May;9(5):545-53. doi: 10.1016/s1074-5521(02)00142-4. Chem Biol. 2002. PMID: 12031661 Review.

8

X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB).

Sridharan S, Wang L, Brown AK, Dover LG, Kremer L, Besra GS, Sacchettini JC. Sridharan S, et al. Among authors: dover lg. J Mol Biol. 2007 Feb 16;366(2):469-80. doi: 10.1016/j.jmb.2006.11.006. Epub 2006 Nov 7. J Mol Biol. 2007. PMID: 17174327 Free PMC article.

9

Mechanism of thioamide drug action against tuberculosis and leprosy.

Wang F, Langley R, Gulten G, Dover LG, Besra GS, Jacobs WR Jr, Sacchettini JC. Wang F, et al. Among authors: dover lg. J Exp Med. 2007 Jan 22;204(1):73-8. doi: 10.1084/jem.20062100. Epub 2007 Jan 16. J Exp Med. 2007. PMID: 17227913 Free PMC article.

10

Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase.

Kremer L, Dover LG, Morehouse C, Hitchin P, Everett M, Morris HR, Dell A, Brennan PJ, McNeil MR, Flaherty C, Duncan K, Besra GS. Kremer L, et al. Among authors: dover lg. J Biol Chem. 2001 Jul 13;276(28):26430-40. doi: 10.1074/jbc.M102022200. Epub 2001 Apr 13. J Biol Chem. 2001. PMID: 11304545 Free article.

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