Nagar B - Search Results

1

Structural basis for the autoinhibition of c-Abl tyrosine kinase.

Nagar B, Hantschel O, Young MA, Scheffzek K, Veach D, Bornmann W, Clarkson B, Superti-Furga G, Kuriyan J. Nagar B, et al. Cell. 2003 Mar 21;112(6):859-71. doi: 10.1016/s0092-8674(03)00194-6. Cell. 2003. PMID: 12654251 Free article.

2

Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571).

Nagar B, Bornmann WG, Pellicena P, Schindler T, Veach DR, Miller WT, Clarkson B, Kuriyan J. Nagar B, et al. Cancer Res. 2002 Aug 1;62(15):4236-43. Cancer Res. 2002. PMID: 12154025

3

Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases.

Wisniewski D, Lambek CL, Liu C, Strife A, Veach DR, Nagar B, Young MA, Schindler T, Bornmann WG, Bertino JR, Kuriyan J, Clarkson B. Wisniewski D, et al. Among authors: nagar b. Cancer Res. 2002 Aug 1;62(15):4244-55. Cancer Res. 2002. PMID: 12154026

4

Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia.

Shah NP, Nicoll JM, Nagar B, Gorre ME, Paquette RL, Kuriyan J, Sawyers CL. Shah NP, et al. Among authors: nagar b. Cancer Cell. 2002 Aug;2(2):117-25. doi: 10.1016/s1535-6108(02)00096-x. Cancer Cell. 2002. PMID: 12204532 Free article.

5

A myristoyl/phosphotyrosine switch regulates c-Abl.

Hantschel O, Nagar B, Guettler S, Kretzschmar J, Dorey K, Kuriyan J, Superti-Furga G. Hantschel O, et al. Among authors: nagar b. Cell. 2003 Mar 21;112(6):845-57. doi: 10.1016/s0092-8674(03)00191-0. Cell. 2003. PMID: 12654250 Free article.

6

Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase.

Nagar B, Hantschel O, Seeliger M, Davies JM, Weis WI, Superti-Furga G, Kuriyan J. Nagar B, et al. Mol Cell. 2006 Mar 17;21(6):787-98. doi: 10.1016/j.molcel.2006.01.035. Mol Cell. 2006. PMID: 16543148 Free article.

7

c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a distributed thermodynamic penalty.

Seeliger MA, Nagar B, Frank F, Cao X, Henderson MN, Kuriyan J. Seeliger MA, et al. Among authors: nagar b. Structure. 2007 Mar;15(3):299-311. doi: 10.1016/j.str.2007.01.015. Structure. 2007. PMID: 17355866 Free article.

8

Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS.

Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J. Margarit SM, et al. Among authors: nagar b. Cell. 2003 Mar 7;112(5):685-95. doi: 10.1016/s0092-8674(03)00149-1. Cell. 2003. PMID: 12628188 Free article.

9

Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless.

Sondermann H, Nagar B, Bar-Sagi D, Kuriyan J. Sondermann H, et al. Among authors: nagar b. Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16632-7. doi: 10.1073/pnas.0508315102. Epub 2005 Nov 2. Proc Natl Acad Sci U S A. 2005. PMID: 16267129 Free PMC article.

10

Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A.

Gorelik A, Illes K, Superti-Furga G, Nagar B. Gorelik A, et al. Among authors: nagar b. J Biol Chem. 2016 Mar 18;291(12):6376-85. doi: 10.1074/jbc.M115.711085. Epub 2016 Jan 20. J Biol Chem. 2016. PMID: 26792860 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

101 results

Search Page

Filters