Stirling DI - Search Results

1

Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs.

Schafer PH, Gandhi AK, Loveland MA, Chen RS, Man HW, Schnetkamp PP, Wolbring G, Govinda S, Corral LG, Payvandi F, Muller GW, Stirling DI. Schafer PH, et al. Among authors: stirling di. J Pharmacol Exp Ther. 2003 Jun;305(3):1222-32. doi: 10.1124/jpet.102.048496. Epub 2003 Mar 20. J Pharmacol Exp Ther. 2003. PMID: 12649301

2

Alpha-fluoro-substituted thalidomide analogues.

Man HW, Corral LG, Stirling DI, Muller GW. Man HW, et al. Among authors: stirling di. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3415-7. doi: 10.1016/s0960-894x(03)00778-9. Bioorg Med Chem Lett. 2003. PMID: 14505639

3

Immunomodulatory drugs inhibit expression of cyclooxygenase-2 from TNF-alpha, IL-1beta, and LPS-stimulated human PBMC in a partially IL-10-dependent manner.

Payvandi F, Wu L, Haley M, Schafer PH, Zhang LH, Chen RS, Muller GW, Stirling DI. Payvandi F, et al. Among authors: stirling di. Cell Immunol. 2004 Aug;230(2):81-8. doi: 10.1016/j.cellimm.2004.09.003. Cell Immunol. 2004. PMID: 15598423

4

Immunomodulatory drugs (IMiDs) increase the production of IL-2 from stimulated T cells by increasing PKC-theta activation and enhancing the DNA-binding activity of AP-1 but not NF-kappaB, OCT-1, or NF-AT.

Payvandi F, Wu L, Naziruddin SD, Haley M, Parton A, Schafer PH, Chen RS, Muller GW, Hughes CC, Stirling DI. Payvandi F, et al. Among authors: stirling di. J Interferon Cytokine Res. 2005 Oct;25(10):604-16. doi: 10.1089/jir.2005.25.604. J Interferon Cytokine Res. 2005. PMID: 16241859

5

lenalidomide enhances natural killer cell and monocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20+ tumor cells.

Wu L, Adams M, Carter T, Chen R, Muller G, Stirling D, Schafer P, Bartlett JB. Wu L, et al. Clin Cancer Res. 2008 Jul 15;14(14):4650-7. doi: 10.1158/1078-0432.CCR-07-4405. Clin Cancer Res. 2008. PMID: 18628480

6

Chiral inversion of the second generation IMiD CC-4047 (ACTIMID ) in human plasma and phosphate-buffered saline.

Teo SK, Chen Y, Muller GW, Chen RS, Thomas SD, Stirling DI, Chandula RS. Teo SK, et al. Among authors: stirling di. Chirality. 2003 May 5;15(4):348-51. doi: 10.1002/chir.10221. Chirality. 2003. PMID: 12666243

7

The synthetic compound CC-5079 is a potent inhibitor of tubulin polymerization and tumor necrosis factor-alpha production with antitumor activity.

Zhang LH, Wu L, Raymon HK, Chen RS, Corral L, Shirley MA, Narla RK, Gamez J, Muller GW, Stirling DI, Bartlett JB, Schafer PH, Payvandi F. Zhang LH, et al. Among authors: stirling di. Cancer Res. 2006 Jan 15;66(2):951-9. doi: 10.1158/0008-5472.CAN-05-2083. Cancer Res. 2006. PMID: 16424030

8

Lenalidomide inhibits proliferation of Namalwa CSN.70 cells and interferes with Gab1 phosphorylation and adaptor protein complex assembly.

Gandhi AK, Kang J, Naziruddin S, Parton A, Schafer PH, Stirling DI. Gandhi AK, et al. Among authors: stirling di. Leuk Res. 2006 Jul;30(7):849-58. doi: 10.1016/j.leukres.2006.01.010. Epub 2006 Feb 21. Leuk Res. 2006. PMID: 16494942

9

The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions.

Lu L, Payvandi F, Wu L, Zhang LH, Hariri RJ, Man HW, Chen RS, Muller GW, Hughes CC, Stirling DI, Schafer PH, Bartlett JB. Lu L, et al. Among authors: stirling di. Microvasc Res. 2009 Mar;77(2):78-86. doi: 10.1016/j.mvr.2008.08.003. Epub 2008 Sep 4. Microvasc Res. 2009. PMID: 18805433

10

Potential new therapeutics for Waldenstrom's macroglobulinemia.

Zeldis JB, Schafer PH, Bennett BL, Mercurio F, Stirling DI. Zeldis JB, et al. Among authors: stirling di. Semin Oncol. 2003 Apr;30(2):275-81. doi: 10.1053/sonc.2003.50078. Semin Oncol. 2003. PMID: 12720152 Review.

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