Hohl M - Search Results

1

Structural determinants for substrate binding and catalysis by the structure-specific endonuclease XPG.

Hohl M, Thorel F, Clarkson SG, Schärer OD. Hohl M, et al. J Biol Chem. 2003 May 23;278(21):19500-8. doi: 10.1074/jbc.M213155200. Epub 2003 Mar 18. J Biol Chem. 2003. PMID: 12644470 Free article.

2

The spacer region of XPG mediates recruitment to nucleotide excision repair complexes and determines substrate specificity.

Dunand-Sauthier I, Hohl M, Thorel F, Jaquier-Gubler P, Clarkson SG, Schärer OD. Dunand-Sauthier I, et al. Among authors: hohl m. J Biol Chem. 2005 Feb 25;280(8):7030-7. doi: 10.1074/jbc.M412228200. Epub 2004 Dec 7. J Biol Chem. 2005. PMID: 15590680 Free article.

3

Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity.

Hohl M, Dunand-Sauthier I, Staresincic L, Jaquier-Gubler P, Thorel F, Modesti M, Clarkson SG, Schärer OD. Hohl M, et al. Nucleic Acids Res. 2007;35(9):3053-63. doi: 10.1093/nar/gkm092. Epub 2007 Apr 22. Nucleic Acids Res. 2007. PMID: 17452369 Free PMC article.

4

The telomere-binding protein Rif2 and ATP-bound Rad50 have opposing roles in the activation of yeast Tel1^ATM kinase.

Hailemariam S, De Bona P, Galletto R, Hohl M, Petrini JH, Burgers PM. Hailemariam S, et al. Among authors: hohl m. J Biol Chem. 2019 Dec 6;294(49):18846-18852. doi: 10.1074/jbc.RA119.011077. Epub 2019 Oct 22. J Biol Chem. 2019. PMID: 31640985 Free PMC article.

5

A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans.

Chansel-Da Cruz M, Hohl M, Ceppi I, Kermasson L, Maggiorella L, Modesti M, de Villartay JP, Ileri T, Cejka P, Petrini JHJ, Revy P. Chansel-Da Cruz M, et al. Among authors: hohl m. Cell Rep. 2020 Dec 29;33(13):108559. doi: 10.1016/j.celrep.2020.108559. Cell Rep. 2020. PMID: 33378670 Free PMC article.

6

The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.

Roset R, Inagaki A, Hohl M, Brenet F, Lafrance-Vanasse J, Lange J, Scandura JM, Tainer JA, Keeney S, Petrini JH. Roset R, et al. Among authors: hohl m. Genes Dev. 2014 Mar 1;28(5):451-62. doi: 10.1101/gad.236745.113. Epub 2014 Feb 14. Genes Dev. 2014. PMID: 24532689 Free PMC article.

7

The Rad50 coiled-coil domain is indispensable for Mre11 complex functions.

Hohl M, Kwon Y, Galván SM, Xue X, Tous C, Aguilera A, Sung P, Petrini JH. Hohl M, et al. Nat Struct Mol Biol. 2011 Sep 4;18(10):1124-31. doi: 10.1038/nsmb.2116. Nat Struct Mol Biol. 2011. PMID: 21892167 Free PMC article.

8

Cohesin association to replication sites depends on rad50 and promotes fork restart.

Tittel-Elmer M, Lengronne A, Davidson MB, Bacal J, François P, Hohl M, Petrini JHJ, Pasero P, Cobb JA. Tittel-Elmer M, et al. Among authors: hohl m. Mol Cell. 2012 Oct 12;48(1):98-108. doi: 10.1016/j.molcel.2012.07.004. Epub 2012 Aug 9. Mol Cell. 2012. PMID: 22885006 Free PMC article.

9

Eukaryotic Rad50 functions as a rod-shaped dimer.

Park YB, Hohl M, Padjasek M, Jeong E, Jin KS, Krężel A, Petrini JH, Cho Y. Park YB, et al. Among authors: hohl m. Nat Struct Mol Biol. 2017 Mar;24(3):248-257. doi: 10.1038/nsmb.3369. Epub 2017 Jan 30. Nat Struct Mol Biol. 2017. PMID: 28134932 Free PMC article.

10

Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis.

Hohl M, Mojumdar A, Hailemariam S, Kuryavyi V, Ghisays F, Sorenson K, Chang M, Taylor BS, Patel DJ, Burgers PM, Cobb JA, Petrini JHJ. Hohl M, et al. PLoS Genet. 2020 Mar 18;16(3):e1008422. doi: 10.1371/journal.pgen.1008422. eCollection 2020 Mar. PLoS Genet. 2020. PMID: 32187176 Free PMC article.

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