Sakaeda T - Search Results

1

Gene expression profiles of ABC transporters and cytochrome P450 3A in Caco-2 and human colorectal cancer cell lines.

Nakumura T, Sakaeda T, Ohmoto N, Moriya Y, Komoto C, Shirakawa T, Gotoh A, Matsuo M, Okmura K. Nakumura T, et al. Among authors: sakaeda t. Pharm Res. 2003 Feb;20(2):324-7. doi: 10.1023/a:1022251910820. Pharm Res. 2003. PMID: 12636175

2

Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas.

Nakamura T, Sakaeda T, Ohmoto N, Tamura T, Aoyama N, Shirakawa T, Kamigaki T, Nakamura T, Kim KI, Kim SR, Kuroda Y, Matsuo M, Kasuga M, Okumura K. Nakamura T, et al. Among authors: sakaeda t. Drug Metab Dispos. 2002 Jan;30(1):4-6. doi: 10.1124/dmd.30.1.4. Drug Metab Dispos. 2002. PMID: 11744604

3

MDR1 up-regulated by apoptotic stimuli suppresses apoptotic signaling.

Sakaeda T, Nakamura T, Hirai M, Kimura T, Wada A, Yagami T, Kobayashi H, Nagata S, Okamura N, Yoshikawa T, Shirakawa T, Gotoh A, Matsuo M, Okumura K. Sakaeda T, et al. Pharm Res. 2002 Sep;19(9):1323-9. doi: 10.1023/a:1020302825511. Pharm Res. 2002. PMID: 12403069

4

Effects of reactive oxygen species on cell proliferation and death in HeLa cells and its MDR1-overexpressing derivative cell line.

Liu YW, Sakaeda T, Takara K, Nakamura T, Ohmoto N, Komoto C, Kobayashi H, Yagami T, Okamura N, Okumura K. Liu YW, et al. Among authors: sakaeda t. Biol Pharm Bull. 2003 Feb;26(2):278-81. doi: 10.1248/bpb.26.278. Biol Pharm Bull. 2003. PMID: 12576695 Free article.

5

Chemosensitivity assessed by collagen gel droplet embedded culture drug sensitivity test, and MDR1, MRP1, and MRP2 mRNA expression in human colorectal adenocarcinomas.

Nakahara T, Sakaeda T, Nakamura T, Tamura T, Nishioka C, Aoyama N, Okamura N, Shirakawa T, Gotoh A, Kamigaki T, Ohno M, Kuroda Y, Matsuo M, Kasuga M, Okumura K. Nakahara T, et al. Among authors: sakaeda t. Pharm Res. 2004 Mar;21(3):406-12. doi: 10.1023/B:PHAM.0000019292.03875.3e. Pharm Res. 2004. PMID: 15070089

6

EGFR mRNA is upregulated, but somatic mutations of the gene are hardly found in renal cell carcinoma in Japanese patients.

Sakaeda T, Okamura N, Gotoh A, Shirakawa T, Terao S, Morioka M, Tokui K, Tanaka H, Nakamura T, Yagi M, Nishimura Y, Yokoyama M, Okumura K. Sakaeda T, et al. Pharm Res. 2005 Oct;22(10):1757-61. doi: 10.1007/s11095-005-7094-2. Epub 2005 Sep 22. Pharm Res. 2005. PMID: 16180134

7

Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport.

Sakaeda T, Fujino H, Komoto C, Kakumoto M, Jin JS, Iwaki K, Nishiguchi K, Nakamura T, Okamura N, Okumura K. Sakaeda T, et al. Pharm Res. 2006 Mar;23(3):506-12. doi: 10.1007/s11095-005-9371-5. Epub 2006 Jan 1. Pharm Res. 2006. PMID: 16388406

8

Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.

Nakamura T, Sakaeda T, Horinouchi M, Tamura T, Aoyama N, Shirakawa T, Matsuo M, Kasuga M, Okumura K. Nakamura T, et al. Among authors: sakaeda t. Clin Pharmacol Ther. 2002 Apr;71(4):297-303. doi: 10.1067/mcp.2002.122055. Clin Pharmacol Ther. 2002. PMID: 11956513

9

Cytotoxic effects of 27 anticancer drugs in HeLa and MDR1-overexpressing derivative cell lines.

Takara K, Sakaeda T, Yagami T, Kobayashi H, Ohmoto N, Horinouchi M, Nishiguchi K, Okumura K. Takara K, et al. Among authors: sakaeda t. Biol Pharm Bull. 2002 Jun;25(6):771-8. doi: 10.1248/bpb.25.771. Biol Pharm Bull. 2002. PMID: 12081145 Free article.

10

Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression.

Takara K, Sakaeda T, Tanigawara Y, Nishiguchi K, Ohmoto N, Horinouchi M, Komada F, Ohnishi N, Yokoyama T, Okumura K. Takara K, et al. Among authors: sakaeda t. Eur J Pharm Sci. 2002 Aug;16(3):159-65. doi: 10.1016/s0928-0987(02)00082-9. Eur J Pharm Sci. 2002. PMID: 12128170

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