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Page 1
Synthesis and biological activity of analogues of the antidiabetic/antiobesity agent 3-guanidinopropionic acid: discovery of a novel aminoguanidinoacetic acid antidiabetic agent.
Larsen SD, Connell MA, Cudahy MM, Evans BR, May PD, Meglasson MD, O'Sullivan TJ, Schostarez HJ, Sih JC, Stevens FC, Tanis SP, Tegley CM, Tucker JA, Vaillancourt VA, Vidmar TJ, Watt W, Yu JH. Larsen SD, et al. Among authors: schostarez hj. J Med Chem. 2001 Apr 12;44(8):1217-30. doi: 10.1021/jm000095f. J Med Chem. 2001. PMID: 11312922
Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action.
Bleasdale JE, Ogg D, Palazuk BJ, Jacob CS, Swanson ML, Wang XY, Thompson DP, Conradi RA, Mathews WR, Laborde AL, Stuchly CW, Heijbel A, Bergdahl K, Bannow CA, Smith CW, Svensson C, Liljebris C, Schostarez HJ, May PD, Stevens FC, Larsen SD. Bleasdale JE, et al. Among authors: schostarez hj. Biochemistry. 2001 May 15;40(19):5642-54. doi: 10.1021/bi002865v. Biochemistry. 2001. PMID: 11341829
Synthesis of a series of stromelysin-selective thiadiazole urea matrix metalloproteinase inhibitors.
Jacobsen EJ, Mitchell MA, Hendges SK, Belonga KL, Skaletzky LL, Stelzer LS, Lindberg TJ, Fritzen EL, Schostarez HJ, O'Sullivan TJ, Maggiora LL, Stuchly CW, Laborde AL, Kubicek MF, Poorman RA, Beck JM, Miller HR, Petzold GL, Scott PS, Truesdell SE, Wallace TL, Wilks JW, Fisher C, Goodman LV, Kaytes PS, et al. Jacobsen EJ, et al. Among authors: schostarez hj. J Med Chem. 1999 May 6;42(9):1525-36. doi: 10.1021/jm9803222. J Med Chem. 1999. PMID: 10229623
Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity.
Finzel BC, Baldwin ET, Bryant GL Jr, Hess GF, Wilks JW, Trepod CM, Mott JE, Marshall VP, Petzold GL, Poorman RA, O'Sullivan TJ, Schostarez HJ, Mitchell MA. Finzel BC, et al. Among authors: schostarez hj. Protein Sci. 1998 Oct;7(10):2118-26. doi: 10.1002/pro.5560071008. Protein Sci. 1998. PMID: 9792098 Free PMC article.
15 results