Willson TM - Search Results

1

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.

Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT. Maglich JM, et al. Among authors: willson tm. J Biol Chem. 2003 May 9;278(19):17277-83. doi: 10.1074/jbc.M300138200. Epub 2003 Feb 27. J Biol Chem. 2003. PMID: 12611900 Free article.

2

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma).

Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. Lehmann JM, et al. Among authors: willson tm. J Biol Chem. 1995 Jun 2;270(22):12953-6. doi: 10.1074/jbc.270.22.12953. J Biol Chem. 1995. PMID: 7768881 Free article.

3

3-[4-(1,2-Diphenylbut-1-enyl)phenyl]acrylic acid: a non-steroidal estrogen with functional selectivity for bone over uterus in rats.

Willson TM, Henke BR, Momtahen TM, Charifson PS, Batchelor KW, Lubahn DB, Moore LB, Oliver BB, Sauls HR, Triantafillou JA, et al. Willson TM, et al. J Med Chem. 1994 May 27;37(11):1550-2. doi: 10.1021/jm00037a002. J Med Chem. 1994. PMID: 8201587 No abstract available.

4

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation.

Kliewer SA, Lenhard JM, Willson TM, Patel I, Morris DC, Lehmann JM. Kliewer SA, et al. Among authors: willson tm. Cell. 1995 Dec 1;83(5):813-9. doi: 10.1016/0092-8674(95)90194-9. Cell. 1995. PMID: 8521498 Free article.

5

The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones.

Willson TM, Cobb JE, Cowan DJ, Wiethe RW, Correa ID, Prakash SR, Beck KD, Moore LB, Kliewer SA, Lehmann JM. Willson TM, et al. J Med Chem. 1996 Feb 2;39(3):665-8. doi: 10.1021/jm950395a. J Med Chem. 1996. PMID: 8576907 No abstract available.

6

3-[2-(N-phenylacetamide)]-1,5-benzodiazepines: orally active, binding selective CCK-A agonists.

Willson TM, Henke BR, Momtahen TM, Myers PL, Sugg EE, Unwalla RJ, Croom DK, Dougherty RW, Grizzle MK, Johnson MF, Queen KL, Rimele TJ, Yingling JD, James MK. Willson TM, et al. J Med Chem. 1996 Jul 19;39(15):3030-4. doi: 10.1021/jm960205b. J Med Chem. 1996. PMID: 8709137

7

Discovery of 1,5-benzodiazepines with peripheral cholecystokinin (CCK-A) receptor agonist activity (II): Optimization of the C3 amino substituent.

Hirst GC, Aquino C, Birkemo L, Croom DK, Dezube M, Dougherty RW Jr, Ervin GN, Grizzle MK, Henke B, James MK, Johnson MF, Momtahen T, Queen KL, Sherrill RG, Szewczyk J, Willson TM, Sugg EE. Hirst GC, et al. Among authors: willson tm. J Med Chem. 1996 Dec 20;39(26):5236-45. doi: 10.1021/jm9601664. J Med Chem. 1996. PMID: 8978852

8

Discovery of ligands for the nuclear peroxisome proliferator-activated receptors.

Willson TM, Lehmann JM, Kliewer SA. Willson TM, et al. Ann N Y Acad Sci. 1996 Dec 27;804:276-83. doi: 10.1111/j.1749-6632.1996.tb18622.x. Ann N Y Acad Sci. 1996. PMID: 8993550

9

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway.

Lehmann JM, Kliewer SA, Moore LB, Smith-Oliver TA, Oliver BB, Su JL, Sundseth SS, Winegar DA, Blanchard DE, Spencer TA, Willson TM. Lehmann JM, et al. Among authors: willson tm. J Biol Chem. 1997 Feb 7;272(6):3137-40. doi: 10.1074/jbc.272.6.3137. J Biol Chem. 1997. PMID: 9013544 Free article.

10

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma.

Kliewer SA, Sundseth SS, Jones SA, Brown PJ, Wisely GB, Koble CS, Devchand P, Wahli W, Willson TM, Lenhard JM, Lehmann JM. Kliewer SA, et al. Among authors: willson tm. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4318-23. doi: 10.1073/pnas.94.9.4318. Proc Natl Acad Sci U S A. 1997. PMID: 9113987 Free PMC article.

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