Parkinson JF - Search Results

1

Pharmacological interference with dimerization of human neuronal nitric-oxide synthase expressed in adenovirus-infected DLD-1 cells.

Habisch HJ, Gorren AC, Liang H, Venema RC, Parkinson JF, Schmidt K, Mayer B. Habisch HJ, et al. Among authors: parkinson jf. Mol Pharmacol. 2003 Mar;63(3):682-9. doi: 10.1124/mol.63.3.682. Mol Pharmacol. 2003. PMID: 12606778

2

Mechanistic studies with potent and selective inducible nitric-oxide synthase dimerization inhibitors.

Blasko E, Glaser CB, Devlin JJ, Xia W, Feldman RI, Polokoff MA, Phillips GB, Whitlow M, Auld DS, McMillan K, Ghosh S, Stuehr DJ, Parkinson JF. Blasko E, et al. Among authors: parkinson jf. J Biol Chem. 2002 Jan 4;277(1):295-302. doi: 10.1074/jbc.M105691200. Epub 2001 Oct 31. J Biol Chem. 2002. PMID: 11689556 Free article.

3

Design, synthesis, and activity of 2-imidazol-1-ylpyrimidine derived inducible nitric oxide synthase dimerization inhibitors.

Davey DD, Adler M, Arnaiz D, Eagen K, Erickson S, Guilford W, Kenrick M, Morrissey MM, Ohlmeyer M, Pan G, Paradkar VM, Parkinson J, Polokoff M, Saionz K, Santos C, Subramanyam B, Vergona R, Wei RG, Whitlow M, Ye B, Zhao ZS, Devlin JJ, Phillips G. Davey DD, et al. J Med Chem. 2007 Mar 22;50(6):1146-57. doi: 10.1021/jm061319i. Epub 2007 Feb 23. J Med Chem. 2007. PMID: 17315988

4

The rational design of inhibitors of nitric oxide formation by inducible nitric oxide synthase.

Whitlow M, Adler M, Davey D, Huang Q, Koovakkat S, Parkinson JF, Pham E, Polokoff M, Xu W, Yuan S, Phillips G. Whitlow M, et al. Among authors: parkinson jf. Bioorg Med Chem Lett. 2007 May 1;17(9):2505-8. doi: 10.1016/j.bmcl.2007.02.018. Epub 2007 Feb 9. Bioorg Med Chem Lett. 2007. PMID: 17336523

5

Quantitative measurement for endothelial constitutive nitric oxide synthase in cultured human endothelial cells.

Aberle S, Young TA, Medberry P, Parkinson J, Rubanyi GM, Kauser K. Aberle S, et al. Nitric Oxide. 1997 Jun;1(3):226-33. doi: 10.1006/niox.1997.0129. Nitric Oxide. 1997. PMID: 9704584

6

Effects of selective inhibitors of nitric oxide synthase-2 dimerization on acute cardiac allograft rejection.

Szabolcs MJ, Sun J, Ma N, Albala A, Sciacca RR, Philips GB, Parkinson J, Edwards N, Cannon PJ. Szabolcs MJ, et al. Circulation. 2002 Oct 29;106(18):2392-6. doi: 10.1161/01.cir.0000034719.08848.26. Circulation. 2002. PMID: 12403672

7

Inducible nitric oxide synthase dimerization inhibitor prevents cardiovascular and renal morbidity in sheep with combined burn and smoke inhalation injury.

Enkhbaatar P, Murakami K, Shimoda K, Mizutani A, Traber L, Phillips G, Parkinson J, Salsbury JR, Biondo N, Schmalstieg F, Burke A, Cox R, Hawkins H, Herndon D, Traber D. Enkhbaatar P, et al. Am J Physiol Heart Circ Physiol. 2003 Dec;285(6):H2430-6. doi: 10.1152/ajpheart.00055.2003. Epub 2003 Aug 14. Am J Physiol Heart Circ Physiol. 2003. PMID: 12919929 Free article.

8

Increased nitric oxide accounts for decreased basal vascular tone and responsiveness in the resistance vessels of high-cholesterol-fed rabbits.

Fitch R, Da Cunha V, Kauser K, Dole W, Parkinson J, Vergona R, Sullivan ME, Wang YX. Fitch R, et al. Pharmacology. 2001;63(4):220-7. doi: 10.1159/000056137. Pharmacology. 2001. PMID: 11729360

9

Visualizing inducible nitric-oxide synthase in living cells with a heme-binding fluorescent inhibitor.

Panda K, Chawla-Sarkar M, Santos C, Koeck T, Erzurum SC, Parkinson JF, Stuehr DJ. Panda K, et al. Among authors: parkinson jf. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10117-22. doi: 10.1073/pnas.0408972102. Epub 2005 Jul 8. Proc Natl Acad Sci U S A. 2005. PMID: 16006534 Free PMC article.

10

Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis.

Brenner T, Brocke S, Szafer F, Sobel RA, Parkinson JF, Perez DH, Steinman L. Brenner T, et al. Among authors: parkinson jf. J Immunol. 1997 Mar 15;158(6):2940-6. J Immunol. 1997. PMID: 9058833

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