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In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis.
Sekurova ON, Brautaset T, Sletta H, Borgos SE, Jakobsen M ØM, Ellingsen TE, Strøm AR, Valla S, Zotchev SB. Sekurova ON, et al. Among authors: borgos se. J Bacteriol. 2004 Mar;186(5):1345-54. doi: 10.1128/JB.186.5.1345-1354.2004. J Bacteriol. 2004. PMID: 14973031 Free PMC article.
Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin.
Sletta H, Borgos SE, Bruheim P, Sekurova ON, Grasdalen H, Aune R, Ellingsen TE, Zotchev SB. Sletta H, et al. Among authors: borgos se. Antimicrob Agents Chemother. 2005 Nov;49(11):4576-83. doi: 10.1128/AAC.49.11.4576-4583.2005. Antimicrob Agents Chemother. 2005. PMID: 16251298 Free PMC article.
Initiation of polyene macrolide biosynthesis: interplay between polyketide synthase domains and modules as revealed via domain swapping, mutagenesis, and heterologous complementation.
Heia S, Borgos SE, Sletta H, Escudero L, Seco EM, Malpartida F, Ellingsen TE, Zotchev SB. Heia S, et al. Among authors: borgos se. Appl Environ Microbiol. 2011 Oct;77(19):6982-90. doi: 10.1128/AEM.05781-11. Epub 2011 Aug 5. Appl Environ Microbiol. 2011. PMID: 21821762 Free PMC article.
34 results