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Efficient synthesis of NK(1) receptor antagonist aprepitant using a crystallization-induced diastereoselective transformation.
Brands KM, Payack JF, Rosen JD, Nelson TD, Candelario A, Huffman MA, Zhao MM, Li J, Craig B, Song ZJ, Tschaen DM, Hansen K, Devine PN, Pye PJ, Rossen K, Dormer PG, Reamer RA, Welch CJ, Mathre DJ, Tsou NN, McNamara JM, Reider PJ. Brands KM, et al. Among authors: reamer ra. J Am Chem Soc. 2003 Feb 26;125(8):2129-35. doi: 10.1021/ja027458g. J Am Chem Soc. 2003. PMID: 12590540
An efficient asymmetric synthesis of an estrogen receptor modulator by sulfoxide-directed borane reduction.
Song ZJ, King AO, Waters MS, Lang F, Zewge D, Bio M, Leazer JL Jr, Javadi G, Kassim A, Tschaen DM, Reamer RA, Rosner T, Chilenski JR, Mathre DJ, Volante RP, Tillyer R. Song ZJ, et al. Among authors: reamer ra. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5776-81. doi: 10.1073/pnas.0307415101. Epub 2004 Apr 12. Proc Natl Acad Sci U S A. 2004. PMID: 15079059 Free PMC article.
Highly Chemoselective Trichloroacetimidate-Mediated Alkylation of Ascomycin: A Convergent, Practical Synthesis of the Immunosuppressant L-733,725.
Song Z, DeMarco A, Zhao M, Corley EG, Thompson AS, McNamara J, Li Y, Rieger D, Sohar P, Mathre DJ, Tschaen DM, Reamer RA, Huntington MF, Ho GJ, Tsay FR, Emerson K, Shuman R, Grabowski EJ, Reider PJ. Song Z, et al. Among authors: reamer ra. J Org Chem. 1999 Mar 19;64(6):1859-1867. doi: 10.1021/jo981805g. J Org Chem. 1999. PMID: 11674275
Practical synthesis of a potent hepatitis C virus RNA replication inhibitor.
Bio MM, Xu F, Waters M, Williams JM, Savary KA, Cowden CJ, Yang C, Buck E, Song ZJ, Tschaen DM, Volante RP, Reamer RA, Grabowski EJ. Bio MM, et al. Among authors: reamer ra. J Org Chem. 2004 Sep 17;69(19):6257-66. doi: 10.1021/jo0491096. J Org Chem. 2004. PMID: 15357584
69 results