Brands KM - Search Results

1

Efficient synthesis of NK(1) receptor antagonist aprepitant using a crystallization-induced diastereoselective transformation.

Brands KM, Payack JF, Rosen JD, Nelson TD, Candelario A, Huffman MA, Zhao MM, Li J, Craig B, Song ZJ, Tschaen DM, Hansen K, Devine PN, Pye PJ, Rossen K, Dormer PG, Reamer RA, Welch CJ, Mathre DJ, Tsou NN, McNamara JM, Reider PJ. Brands KM, et al. J Am Chem Soc. 2003 Feb 26;125(8):2129-35. doi: 10.1021/ja027458g. J Am Chem Soc. 2003. PMID: 12590540

2

Efficient one-pot synthesis of the 2-aminocarbonylpyrrolidin-4-ylthio-containing side chain of the new broad-spectrum carbapenem antibiotic ertapenem.

Brands KM, Jobson RB, Conrad KM, Williams JM, Pipik B, Cameron M, Davies AJ, Houghton PG, Ashwood MS, Cottrell IF, Reamer RA, Kennedy DJ, Dolling UH, Reider PJ. Brands KM, et al. J Org Chem. 2002 Jul 12;67(14):4771-6. doi: 10.1021/jo011170c. J Org Chem. 2002. PMID: 12098287

3

Practical asymmetric synthesis of aprepitant, a potent human NK-1 receptor antagonist, via a stereoselective Lewis acid-catalyzed trans acetalization reaction.

Zhao MM, McNamara JM, Ho GJ, Emerson KM, Song ZJ, Tschaen DM, Brands KM, Dolling UH, Grabowski EJ, Reider PJ, Cottrell IF, Ashwood MS, Bishop BC. Zhao MM, et al. Among authors: brands km. J Org Chem. 2002 Sep 20;67(19):6743-7. doi: 10.1021/jo0203793. J Org Chem. 2002. PMID: 12227806

4

A novel crystallization-induced diastereomeric transformation based on a reversible carbon-sulfur bond formation. Application to the synthesis of a gamma-secretase inhibitor.

Davies AJ, Scott JP, Bishop BC, Brands KM, Brewer SE, Dasilva JO, Dormer PG, Dolling UH, Gibb AD, Hammond DC, Lieberman DR, Palucki M, Payack JF. Davies AJ, et al. Among authors: brands km. J Org Chem. 2007 Jun 22;72(13):4864-71. doi: 10.1021/jo0705925. Epub 2007 May 24. J Org Chem. 2007. PMID: 17521199

5

Reaction development and mechanistic study of a ruthenium catalyzed intramolecular asymmetric reductive amination en route to the dual Orexin inhibitor Suvorexant (MK-4305).

Strotman NA, Baxter CA, Brands KM, Cleator E, Krska SW, Reamer RA, Wallace DJ, Wright TJ. Strotman NA, et al. Among authors: brands km. J Am Chem Soc. 2011 Jun 1;133(21):8362-71. doi: 10.1021/ja202358f. Epub 2011 May 11. J Am Chem Soc. 2011. PMID: 21528938

6

Practical asymmetric synthesis of a gamma-secretase inhibitor exploiting substrate-controlled intramolecular nitrile oxide-olefin cycloaddition.

Scott JP, Oliver SF, Brands KM, Brewer SE, Davies AJ, Gibb AD, Hands D, Keen SP, Sheen FJ, Reamer RA, Wilson RD, Dolling UH. Scott JP, et al. Among authors: brands km. J Org Chem. 2006 Apr 14;71(8):3086-92. doi: 10.1021/jo060033i. J Org Chem. 2006. PMID: 16599604

7

Crystallization-induced diastereomer transformations.

Brands KM, Davies AJ. Brands KM, et al. Chem Rev. 2006 Jul;106(7):2711-33. doi: 10.1021/cr0406864. Chem Rev. 2006. PMID: 16836297 Review. No abstract available.

8

Practical asymmetric synthesis of a non-peptidic alphavbeta3 antagonist.

Keen SP, Cowden CJ, Bishop BC, Brands KM, Davies AJ, Dolling UH, Lieberman DR, Stewart GW. Keen SP, et al. Among authors: brands km. J Org Chem. 2005 Mar 4;70(5):1771-9. doi: 10.1021/jo048082n. J Org Chem. 2005. PMID: 15730300

9

A practical synthesis of a gamma-secretase inhibitor.

Scott JP, Lieberman DR, Beureux OM, Brands KM, Davies AJ, Gibson AW, Hammond DC, McWilliams CJ, Stewart GW, Wilson RD, Dolling UH. Scott JP, et al. Among authors: brands km. J Org Chem. 2007 May 25;72(11):4149-55. doi: 10.1021/jo070407n. Epub 2007 Apr 28. J Org Chem. 2007. PMID: 17465573

10

Practical synthesis of the new carbapenem antibiotic ertapenem sodium.

Williams JM, Brands KM, Skerlj RT, Jobson RB, Marchesini G, Conrad KM, Pipik B, Savary KA, Tsay FR, Houghton PG, Sidler DR, Dolling UH, DiMichele LM, Novak TJ. Williams JM, et al. Among authors: brands km. J Org Chem. 2005 Sep 16;70(19):7479-87. doi: 10.1021/jo0501442. J Org Chem. 2005. PMID: 16149774

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

11 results

Search Page

Filters