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454 results

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Page 1
Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines.
Burgey CS, Robinson KA, Lyle TA, Sanderson PE, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Williams PD, Coburn CA, Dorsey BD, Barrow JC, Stranieri MT, Holahan MA, Sitko GR, Cook JJ, McMasters DR, McDonough CM, Sanders WM, Wallace AA, Clayton FC, Bohn D, Leonard YM, Detwiler TJ Jr, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP. Burgey CS, et al. Among authors: robinson ka. J Med Chem. 2003 Feb 13;46(4):461-73. doi: 10.1021/jm020311f. J Med Chem. 2003. PMID: 12570369
Pharmacokinetic optimization of 3-amino-6-chloropyrazinone acetamide thrombin inhibitors. Implementation of P3 pyridine N-oxides to deliver an orally bioavailable series containing P1 N-benzylamides.
Burgey CS, Robinson KA, Lyle TA, Nantermet PG, Selnick HG, Isaacs RC, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Stranieri MT, Cook JJ, McMasters DR, Pellicore JM, Pal S, Wallace AA, Clayton FC, Bohn D, Welsh DC, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP. Burgey CS, et al. Among authors: robinson ka. Bioorg Med Chem Lett. 2003 Apr 7;13(7):1353-7. doi: 10.1016/s0960-894x(03)00099-4. Bioorg Med Chem Lett. 2003. PMID: 12657281
P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold.
Nantermet PG, Burgey CS, Robinson KA, Pellicore JM, Newton CL, Deng JZ, Selnick HG, Lewis SD, Lucas BJ, Krueger JA, Miller-Stein C, White RB, Wong B, McMasters DR, Wallace AA, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP, Lyle TA. Nantermet PG, et al. Among authors: robinson ka. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2771-5. doi: 10.1016/j.bmcl.2005.03.110. Bioorg Med Chem Lett. 2005. PMID: 15911253
Quantitative assessment of ultrasound microvessel imaging in Crohn's disease: correlation with pathological inflammation.
Lok UW, Tang S, Gong P, Smyrk T, Huang C, DeRuiter RM, Knoll KM, Robinson KA, Sheedy SP, Holmes PM, Zhang J, El Sadaney AO, Harmsen W, Fletcher JG, Knudsen JM, Chen S, Bruining DH. Lok UW, et al. Among authors: robinson ka. Eur Radiol. 2024 Nov 16. doi: 10.1007/s00330-024-11156-x. Online ahead of print. Eur Radiol. 2024. PMID: 39547980
HIPEC for metastatic gastric cancer: Moving the needle towards 3-year survival.
Bhutiani N, Seo YD, Robinson KA, White MG, Ikoma N, Mansfield PF, Li JJ, Murphy MB, Ajani JA, Badgwell BD. Bhutiani N, et al. Among authors: robinson ka. Eur J Surg Oncol. 2025 Jan;51(1):108790. doi: 10.1016/j.ejso.2024.108790. Epub 2024 Oct 25. Eur J Surg Oncol. 2025. PMID: 39489042
454 results