Hazuda DJ - Search Results

1

Design and synthesis of 8-hydroxy-[1,6]naphthyridines as novel inhibitors of HIV-1 integrase in vitro and in infected cells.

Zhuang L, Wai JS, Embrey MW, Fisher TE, Egbertson MS, Payne LS, Guare JP Jr, Vacca JP, Hazuda DJ, Felock PJ, Wolfe AL, Stillmock KA, Witmer MV, Moyer G, Schleif WA, Gabryelski LJ, Leonard YM, Lynch JJ Jr, Michelson SR, Young SD. Zhuang L, et al. Among authors: hazuda dj. J Med Chem. 2003 Feb 13;46(4):453-6. doi: 10.1021/jm025553u. J Med Chem. 2003. PMID: 12570367

2

Inhibition of human immunodeficiency virus integrase by bis-catechols.

LaFemina RL, Graham PL, LeGrow K, Hastings JC, Wolfe A, Young SD, Emini EA, Hazuda DJ. LaFemina RL, et al. Among authors: hazuda dj. Antimicrob Agents Chemother. 1995 Feb;39(2):320-4. doi: 10.1128/AAC.39.2.320. Antimicrob Agents Chemother. 1995. PMID: 7726489 Free PMC article.

3

A novel assay for the DNA strand-transfer reaction of HIV-1 integrase.

Hazuda DJ, Hastings JC, Wolfe AL, Emini EA. Hazuda DJ, et al. Nucleic Acids Res. 1994 Mar 25;22(6):1121-2. doi: 10.1093/nar/22.6.1121. Nucleic Acids Res. 1994. PMID: 8152918 Free PMC article. No abstract available.

4

Viral long terminal repeat substrate binding characteristics of the human immunodeficiency virus type 1 integrase.

Hazuda DJ, Wolfe AL, Hastings JC, Robbins HL, Graham PL, LaFemina RL, Emini EA. Hazuda DJ, et al. J Biol Chem. 1994 Feb 11;269(6):3999-4004. J Biol Chem. 1994. PMID: 8307956 Free article.

5

The role of manganese in promoting multimerization and assembly of human immunodeficiency virus type 1 integrase as a catalytically active complex on immobilized long terminal repeat substrates.

Wolfe AL, Felock PJ, Hastings JC, Blau CU, Hazuda DJ. Wolfe AL, et al. Among authors: hazuda dj. J Virol. 1996 Mar;70(3):1424-32. doi: 10.1128/JVI.70.3.1424-1432.1996. J Virol. 1996. PMID: 8627659 Free PMC article.

6

Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds.

Hazuda D, Felock P, Hastings J, Pramanik B, Wolfe A, Goodarzi G, Vora A, Brackmann K, Grandgenett D. Hazuda D, et al. J Virol. 1997 Jan;71(1):807-11. doi: 10.1128/JVI.71.1.807-811.1997. J Virol. 1997. PMID: 8985421 Free PMC article.

7

Differential divalent cation requirements uncouple the assembly and catalytic reactions of human immunodeficiency virus type 1 integrase.

Hazuda DJ, Felock PJ, Hastings JC, Pramanik B, Wolfe AL. Hazuda DJ, et al. J Virol. 1997 Sep;71(9):7005-11. doi: 10.1128/JVI.71.9.7005-7011.1997. J Virol. 1997. PMID: 9261430 Free PMC article.

8

Discovery and analysis of inhibitors of the human immunodeficiency integrase.

Hazuda D, Felock PJ, Hastings JC, Pramanik B, Wolfe AL. Hazuda D, et al. Drug Des Discov. 1997 May;15(1):17-24. Drug Des Discov. 1997. PMID: 9332828

9

Isolation and characterization of novel human immunodeficiency virus integrase inhibitors from fungal metabolites.

Hazuda D, Blau CU, Felock P, Hastings J, Pramanik B, Wolfe A, Bushman F, Farnet C, Goetz M, Williams M, Silverman K, Lingham R, Singh S. Hazuda D, et al. Antivir Chem Chemother. 1999 Mar;10(2):63-70. doi: 10.1177/095632029901000202. Antivir Chem Chemother. 1999. PMID: 10335400 Free article.

10

Efficiency and fidelity of full-site integration reactions using recombinant simian immunodeficiency virus integrase.

Goodarzi G, Pursley M, Felock P, Witmer M, Hazuda D, Brackmann K, Grandgenett D. Goodarzi G, et al. J Virol. 1999 Oct;73(10):8104-11. doi: 10.1128/JVI.73.10.8104-8111.1999. J Virol. 1999. PMID: 10482559 Free PMC article.

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