Fairlie DP - Search Results

1

Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion.

Williamson AL, Brindley PJ, Abbenante G, Datu BJ, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Zhan B, Loukas A. Williamson AL, et al. Among authors: fairlie dp. J Infect Dis. 2003 Feb 1;187(3):484-94. doi: 10.1086/367708. Epub 2003 Jan 24. J Infect Dis. 2003. PMID: 12552433

2

Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.

Martin JL, Begun J, Schindeler A, Wickramasinghe WA, Alewood D, Alewood PF, Bergman DA, Brinkworth RI, Abbenante G, March DR, Reid RC, Fairlie DP. Martin JL, et al. Among authors: fairlie dp. Biochemistry. 1999 Jun 22;38(25):7978-88. doi: 10.1021/bi990174x. Biochemistry. 1999. PMID: 10387041

3

Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site.

Abbenante G, Kovacs DM, Leung DL, Craik DJ, Tanzi RE, Fairlie DP. Abbenante G, et al. Among authors: fairlie dp. Biochem Biophys Res Commun. 2000 Feb 5;268(1):133-5. doi: 10.1006/bbrc.2000.2098. Biochem Biophys Res Commun. 2000. PMID: 10652226

4

Protease inhibitors: current status and future prospects.

Leung D, Abbenante G, Fairlie DP. Leung D, et al. Among authors: fairlie dp. J Med Chem. 2000 Feb 10;43(3):305-41. doi: 10.1021/jm990412m. J Med Chem. 2000. PMID: 10669559 Review. No abstract available.

5

Conformational selection of inhibitors and substrates by proteolytic enzymes: implications for drug design and polypeptide processing.

Fairlie DP, Tyndall JD, Reid RC, Wong AK, Abbenante G, Scanlon MJ, March DR, Bergman DA, Chai CL, Burkett BA. Fairlie DP, et al. J Med Chem. 2000 Apr 6;43(7):1271-81. doi: 10.1021/jm990315t. J Med Chem. 2000. PMID: 10753465

6

Proteolysis of human hemoglobin by schistosome cathepsin D.

Brindley PJ, Kalinna BH, Wong JY, Bogitsh BJ, King LT, Smyth DJ, Verity CK, Abbenante G, Brinkworth RI, Fairlie DP, Smythe ML, Milburn PJ, Bielefeldt-Ohmann H, Zheng Y, McManus DP. Brindley PJ, et al. Among authors: fairlie dp. Mol Biochem Parasitol. 2001 Jan 15;112(1):103-12. doi: 10.1016/s0166-6851(00)00351-0. Mol Biochem Parasitol. 2001. PMID: 11166391

7

Novel cylindrical, conical, and macrocyclic peptides from the cyclooligomerization of functionalized thiazole amino acids.

Singh Y, Sokolenko N, Kelso MJ, Gahan LR, Abbenante G, Fairlie DP. Singh Y, et al. Among authors: fairlie dp. J Am Chem Soc. 2001 Jan 17;123(2):333-4. doi: 10.1021/ja002666z. J Am Chem Soc. 2001. PMID: 11456521 No abstract available.

8

Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors.

Leung D, Schroder K, White H, Fang NX, Stoermer MJ, Abbenante G, Martin JL, Young PR, Fairlie DP. Leung D, et al. Among authors: fairlie dp. J Biol Chem. 2001 Dec 7;276(49):45762-71. doi: 10.1074/jbc.M107360200. Epub 2001 Oct 1. J Biol Chem. 2001. PMID: 11581268 Free article.

9

Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity.

Williamson AL, Brindley PJ, Abbenante G, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Dalton JP, Loukas A. Williamson AL, et al. Among authors: fairlie dp. FASEB J. 2002 Sep;16(11):1458-60. doi: 10.1096/fj.02-0181fje. Epub 2002 Jul 18. FASEB J. 2002. PMID: 12205047

10

A convergent solution-phase synthesis of the macrocycle Ac-Phe-[Orn-Pro-D-Cha-Trp-Arg], a potent new antiinflammatory drug.

Reid RC, Abbenante G, Taylor SM, Fairlie DP. Reid RC, et al. Among authors: fairlie dp. J Org Chem. 2003 May 30;68(11):4464-71. doi: 10.1021/jo034228r. J Org Chem. 2003. PMID: 12762752

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